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image: Chemogenetics Doesn’t Work Like Many Thought

Chemogenetics Doesn’t Work Like Many Thought

By | August 4, 2017

A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.

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Two freely available databases include data on hundreds of human cancer cell lines. 

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image: Stem Cells Seek Out Tumors Based on Stiffness

Stem Cells Seek Out Tumors Based on Stiffness

By | July 26, 2017

The technique, demonstrated in mice using engineered mesenchymal stem cells, has potential for both diagnosis and treatment.

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image: Stem Cells in the Hypothalamus Slow Aging in Mice

Stem Cells in the Hypothalamus Slow Aging in Mice

By | July 26, 2017

Once implanted into animals’ brains, neural stem cells that secrete microRNA-containing vesicles seem to contribute to an anti-aging effect.

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image: Behavior Circuits Mapped in Whole Fruit Fly Brain

Behavior Circuits Mapped in Whole Fruit Fly Brain

By | July 13, 2017

Using machine learning, researchers have created extensive maps of the neuronal circuits associated with social and locomotion behaviors in the fruit fly. 

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image: Electrical Stimulation Steers Neural Stem Cells

Electrical Stimulation Steers Neural Stem Cells

By | July 3, 2017

Current can guide implanted cells away from rats’ noses toward a region deep in their brains.

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image: Transgenic Mouse Illuminates Melanoma Metastasis

Transgenic Mouse Illuminates Melanoma Metastasis

By | June 28, 2017

Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 

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An analysis of human cancer genome projects uncovers a counterintuitive loss of ribosomal gene copies.

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image: How Roundworms Sleep

How Roundworms Sleep

By | June 22, 2017

When Caenorhabditis elegans surrenders to slumber, the majority of its neurons fall silent.

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image: Gut Feeling

Gut Feeling

By | June 22, 2017

Sensory cells of the mouse intestine let the brain know if certain compounds are present by speaking directly to gut neurons via serotonin.

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    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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