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A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer.

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By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

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image: Rethinking a Cancer Drug Target

Rethinking a Cancer Drug Target

By | March 26, 2017

The results of a CRISPR-Cas9 study suggest that MELK—a protein thought to play a critical role in cancer—is not necessary for cancer cell survival.

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image: Abundant Sequence Errors in Public Databases

Abundant Sequence Errors in Public Databases

By | February 16, 2017

A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.

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image: Toward Killing Cancer with Bacteria

Toward Killing Cancer with Bacteria

By | February 8, 2017

Researchers employ an engineered microbe to destroy tumor cells in mice.

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image: Non-Chromosomal DNA Drives Tumor Evolution

Non-Chromosomal DNA Drives Tumor Evolution

By | February 8, 2017

Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.

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image: Lipids Take the Lead in Metastasis

Lipids Take the Lead in Metastasis

By | January 20, 2017

Researchers find diverse ways that the molecules can regulate cancer’s spread.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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image: Speaking of Science: 2016

Speaking of Science: 2016

By | December 19, 2016

Selected quotes from an eventful year

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A noninvasive microscopy technique that exploits NADH fluorescence enables researchers to observe how mitochondria alter their shape and arrangement in human tissue.

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