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image: Replication Complications

Replication Complications

By | January 18, 2017

An initiative to replicate key findings in cancer biology yields a preliminary conclusion: it’s difficult.

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A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

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image: Exploring the Epigenetics of Ethnicity

Exploring the Epigenetics of Ethnicity

By | January 11, 2017

Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.

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image: As the Brain Ages, Glial-Cell Gene Expression Changes Most

As the Brain Ages, Glial-Cell Gene Expression Changes Most

By | January 10, 2017

Researchers describe how gene expression in different human brain regions is altered with age.

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image: Exome Study Reveals Novel Disease-Linked Alleles

Exome Study Reveals Novel Disease-Linked Alleles

By | December 22, 2016

By combining whole-exome sequencing data with longitudinal electronic health record information for 50,000 individuals, researchers have identified novel disease associations.

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image: New Species of 2016

New Species of 2016

By | December 16, 2016

From a new Tyrannosaurus and many other dinosaurs to all of the living species named this year, researchers continue to chip away at the planet’s unknown biodiversity.

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image: Induced Pluripotent Stem Cells Show Signs of Donor Age

Induced Pluripotent Stem Cells Show Signs of Donor Age

By | December 12, 2016

iPSCs created through the reprogramming of human somatic cells retain genomic marks of the donor’s age.

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image: Phages Carry Antibiotic Resistance Genes

Phages Carry Antibiotic Resistance Genes

By | December 8, 2016

Researchers find evidence of antibiotic resistance genes in the DNA of viruses that infect bacteria.

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image: Controlled Splicing Extends Life Span in Roundworms

Controlled Splicing Extends Life Span in Roundworms

By | December 7, 2016

Increasing the expression of an RNA splicing factor mimics dietary restriction, prolonging life in nematodes. 

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image: Next Generation: Super-Fast Tracking of Single Molecules

Next Generation: Super-Fast Tracking of Single Molecules

By | November 23, 2016

A clever twist on a super-resolution microscopy technique improves the temporal resolution of single-molecule tracking. 

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