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neuroscience

Illustration showing how iGluSnFR3, tracks glutamate release at the synapse level. Upon binding to glutamate, the reporter changes its conformation, intensifying the signal of its fluorescent protein.
Infographic: How a Glutamate Sensor Tracks Synapses
Mariella Bodemeier Loayza Careaga, PhD | Sep 8, 2023 | 1 min read
A third generation glutamate sensor with a fluorescent readout offers insights into neuronal communication.
A rendering of a human brain in blue on a dark background with blue and white lines surrounding the brain to represent the construction of new connections in the brain.
Defying Dogma: Decentralized Translation in Neurons
Danielle Gerhard, PhD | Sep 8, 2023 | 10+ min read
To understand how memories are formed and maintained, neuroscientists travel far beyond the cell body in search of answers.
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
Autophagy and Mitophagy in Neurodegeneration: A Deep Dive
The Scientist and PerkinElmer | 1 min read
Robin Ketteler and Hélène Plun-Favreau discuss the importance of autophagy and mitophagy regulation in neurodegenerative diseases.
Digital illustration of a brain, constructed by tiny dots and lines. Most dots and lines are teal-colored; others are green, yellow, red, and purple to denote areas of activity.
What Was the First Animal to Evolve a Brain?
Ida Emilie Steinmark, PhD | Sep 1, 2023 | 1 min read
In the absence of a precise definition of brain, pinning down its origins is difficult. But scientists have a theory.
The image shows round-shaped glial cells in red and elongated neuronal cells in green surrounding the glial cells.
How Stress Inflames the Gut
Mariella Bodemeier Loayza Careaga, PhD | Sep 1, 2023 | 2 min read
In mice, chronically high levels of stress hormones worsen bowel inflammation.
A Rising Star Launches Brain Power into Outer Space
Science Philosophy in a Flash - A Rising Star Launches Brain Power into Outer Space
Iris Kulbatski, PhD | 1 min read
Alysson Muotri shares how tapping into his inner creative spark fuels his pursuit of science.
Colorful blue and pink low poly side view human brain illustration with connection dots isolated on bright blue background
Cancer Cells Need Fatty Acids to Survive in the Brain
Danielle Gerhard, PhD, Drug Discovery News | Aug 30, 2023 | 3 min read
Using a mouse model of breast cancer brain metastasis, researchers showed that tumor cells require fatty acid synthesis to grow, which offers a potential therapeutic target.
The image illustrates the relationship between the brain and gut in humans.
A Novel Tool to Explore the Gut-brain Connection
Anna Napolitano, PhD | Aug 28, 2023 | 3 min read
Scientists used a vibrating capsule to assess people’s gut sensitivities and understand how the brain interprets these signals.  
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Fortis Life Sciences | 3 min read
Identifying novel biomarkers of Parkinson’s disease enables early diagnosis and treatment monitoring.
A light gray mouse against an orange background listens to tiny headphones
Journey to the Center of the Ear
Niki Spahich, PhD | Aug 28, 2023 | 5 min read
An aqueduct connecting the brain to the ear may make gene therapy for hearing loss less invasive.
MRI images of brains from patients with epilepsy
Defending against Dravet
Aparna Nathan, PhD | Aug 21, 2023 | 3 min read
Gene therapy may be the first step toward curing a rare genetic epilepsy.
The Mosaic Brain
Sejal Davla, PhD | 1 min read
How somatic mutations cause brain diseases
Six black-and-white MRI images of a brain at different cross-sections.
Is DIANA fMRI Data Real?
Ida Emilie Steinmark, PhD | Aug 17, 2023 | 4 min read
New preprints failed to reproduce the buzzy new neuroimaging technique DIANA fMRI, but its inventor remains steadfast.
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
iStock
The Scientist Speaks - Finding that Sweet Spot: Understanding Gut Perception One Cell at a Time
Iris Kulbatski, PhD | 1 min read
Maya Kaelberer discusses her research investigating how sensory cells in the gut guide feeding behavior.
Caenorhabditis elegans, a free-living transparent nematode (roundworm), about 1 mm in length.
The Body, Not the Brain, Regulates Sleep
Rebecca Roberts, PhD | Aug 15, 2023 | 3 min read
Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Visualize Transcript Location with Spatial Biology Techniques
Unraveling the Cellular and Subcellular Landscape Using Spatial Biology
The Scientist and Resolve Biosciences | 1 min read
How to visualize gene expression patterns in situ
Surreal illustration of the mind, represented by a person-shaped iceberg. A scuba diver illuminates the dark side of the iceberg underwater with a flashlight.
Toward Better Biomarkers for Schizophrenia
Deanna MacNeil, PhD | Aug 7, 2023 | 3 min read
Researchers scratch the surface of schizophrenia susceptibility by uncovering DNA methylation differences in neonatal blood samples.
Human finger touching a conceptual image of a brain, triggering an electrical spark.
Shaping Brain Recovery Using Bioelectricity
Iris Kulbatski, PhD | Aug 4, 2023 | 3 min read
Scientists are decoding how electrically stimulating transplanted stem cells helps heal the injured brain.
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