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tag dna methylation histone methylation genetics genomics africa

A view of the nucleus of a cell with DNA in blue, RNA in pink, and associated proteins in yellow and purple
DNA Methylation Influences Replication and Genome Organization
Abby Olena, PhD | Sep 22, 2021 | 3 min read
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Managing Methylation
Karen Zusi | Jan 1, 2016 | 2 min read
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Illustration from the epigenetics and the genome infographic
Infographic: How Epigenetic Marks Can Change the Genome
Katarina Zimmer | Nov 1, 2022 | 2 min read
Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.
Histone Methylation is Making its Mark
Brendan Maher | Jan 26, 2003 | 6 min read
Data derived from the Science Watch/Hot Papers database and the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. M. Lachner et al., "Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins," Nature, 410:116-20, 2001. (Cited in 202 papers) A.J. Bannister et al., "Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain," Nature, 410:120-4, 2001. (Cited in 2
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
DNA Methylation Declines with Age
Sabrina Richards | Jun 11, 2012 | 3 min read
Newborns carry more epigenetic markers than nonagenarians, providing clues to the mechanisms underlying aging.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
DNA Methylation Linked to Memory Loss
Sabrina Richards | Jul 2, 2012 | 3 min read
Scientists find that declining DNA methylation in mouse neurons may cause age-related memory deficits.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

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