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Artist’s rendition of orange DNA coiled around a blue histone protein.
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes
Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes

Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.

Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.

histone methylation, histone modification

early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
The Epigenetic Lnc
Kevin V. Morris | Oct 1, 2012 | 1 min read
Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa
How Longevity Is Passed On
Cristina Luiggi | Oct 19, 2011 | 3 min read
For the first time researchers have shown that epigenetic changes that increase lifespan can be inherited across multiple generations.
Epigenetics—A Primer
Stefan Kubicek | Mar 1, 2011 | 1 min read
There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.
Epigenetics—A Primer
Stefan Kubicek | Mar 1, 2011 | 1 min read
Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin. 
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