neuroscience

Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

In FIRE mice, the lack of microglia causes myelin overgrowth and eventual degeneration, indicating that microglia may contribute to age-related neurodegenerative diseases.

As scientists realize the multifaceted role of mitochondria, some feel that the “powerhouse of the cell” analogy is out of date.

Molecular studies may point to underlying genetics and therapeutic targets.

A bridge between neurons triggers longer, deeper sleep and memory formation in fly larvae.

Intermittent fasting regulates biological time and improves disrupted sleep in an Alzheimer’s disease model.

Division of labor in ant colonies may depend on an enzyme trapped inside the blood-brain barrier.

Some elements of human immune systems serve important functions beyond fighting infections.

Gene reactivation restored hearing after loss in mice, but the timing of intervention is key.

Al dente asparagus stalks may hold the key to successful neural stem cell therapy for repairing injured axons.

Researchers find that the sugar myo-inositol is abundant early in lactation and increases synapse size and abundance in the developing brain.

Researchers integrate scRNA-seq, spatial transcriptomics, and histology imaging data to show that spatial cellular architecture predicts glioblastoma prognosis.

Researchers developed a novel protein fiber that tracks transcriptional events over time in living cells. This could shine a light on gene regulation during development or after cellular perturbations.

During development, neurons trim hundreds of excess axons in an intricately coordinated destructive process.