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cancer, clinical trials

The Little Cell That Could
Megan Scudellari | Jul 1, 2012 | 7 min read
Critics point out that cell therapy has yet to top existing treatments. Biotech companies are setting out to change that—and prove that the technology can revolutionize medicine.
A Plea to the FDA
Cristina Luiggi | Jun 21, 2012 | 1 min read
Protesters crash the BIO conference to protest the delayed approval of a breast cancer drug.
FDA OKs Early Stage Trials
Cristina Luiggi | Jun 5, 2012 | 1 min read
The regulatory agency will allow early-stage breast cancer patients to try experimental drugs previously reserved for those with advanced disease.
Trials Overlook Cancer Spread
Ed Yong | May 30, 2012 | 3 min read
One cancer researcher says that by focusing solely on stalling cancer growth, clinical trials are failing some potentially life-saving drugs that prevent metastasis.
Legislating Negative Result Reporting
Bob Grant | May 7, 2012 | 1 min read
A new bill aims to increase transparency in cancer clinical trials by requiring researchers to divulge all outcomes.
A Universal Cancer Vaccine?
Cristina Luiggi | Apr 10, 2012 | 1 min read
A vaccine that targets 90 percent of all cancers shows promise in early clinical trials.
More Oversight for Omics Tests
N/A | Mar 27, 2012 | 1 min read
A new report outlines ways in which omics-based technologies can be shuttled more safely and effectively from the bench to the clinic.
What it Takes to Develop Better Drugs for Kids
J. Steven Leeder | Mar 1, 2012 | 4 min read
Over the past 15 years, new laws and regulations in the United States and the European Union have expanded to require the inclusion of pediatric patients in clinical drug trials.  
Suspected Effects of Vitamin D
Amy Maxmen | Mar 1, 2012 | 1 min read
Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 
Vitamin D on Trial
Amy Maxmen | Mar 1, 2012 | 10+ min read
Prevention trials for vitamins and supplements are notoriously difficult, but some researchers aren’t giving up on finding proof that vitamin D helps ward off disease.
Electromagnetic Fields Shrink Tumors
Bob Grant | Jan 11, 2012 | 1 min read
New research shows that low-intensity fields can inhibit cancer cell proliferation.
Drug Shortages Plague Research
Rachel Nuwer | Oct 5, 2011 | 2 min read
Dwindling stocks in more than a dozen cancer drugs are delaying clinical trials.
Top 7 in Aging Research
Edyta Zielinska | Sep 13, 2011 | 2 min read
A snapshot of the most highly ranked articles in aging research and related areas, from Faculty of 1000
Duke Sued for Cancer Trial
Jef Akst | Sep 12, 2011 | 1 min read
Cancer patients and families of deceased patients filed a lawsuit against Duke University for clinical trials based on flawed data.
Failed vaccine trial raises questions
Jef Akst | Jun 23, 2011 | 2 min read
In contrast to yesterday’s news about the success of an HPV vaccine program in Australia, an Indian trial of the vaccine is stoking unfounded fear among the public and exposing some questionable ethical standards.
Take Two of These
Bob Grant | Jun 22, 2011 | 6 min read
Drugmakers are teaming up to test the disease-fighting power of combination therapies earlier in the development cycle than ever before.
Drugs target cancer stem cells
Bob Grant | Jun 6, 2011 | 1 min read
New compounds are showing promise in targeting subpopulations of cancer stem cells.
Taking Aim at Melanoma
Keith T. Flaherty | Apr 1, 2011 | 10+ min read
Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.
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