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image: Study Raises Questions About Patient-Derived Xenografts

Study Raises Questions About Patient-Derived Xenografts

By Ashley P. Taylor | October 10, 2017

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.

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image: Gene Drive Limitations

Gene Drive Limitations

By Jef Akst | October 9, 2017

In lab populations of genetically engineered mosquitoes, mutations arose that blocked the gene drive’s spread and restored female fertility.

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Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.

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image: Most Accurate CRISPR Gene Editing Yet

Most Accurate CRISPR Gene Editing Yet

By Kerry Grens | September 22, 2017

A tweaked Cas9 nuclease reduces off-target effects to levels below that of previous versions of the enzyme.

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image: CRISPR Used in Human Embryos to Probe Gene Function

CRISPR Used in Human Embryos to Probe Gene Function

By Ashley P. Taylor | September 20, 2017

OCT4 is necessary for blastocyst formation in the human embryo, researchers report.

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image: Criticism for Craig Venter’s “Face-Prediction” Software

Criticism for Craig Venter’s “Face-Prediction” Software

By Catherine Offord | September 11, 2017

The tool cannot predict a person’s face from DNA, say researchers—including some listed as coauthors on the publication. 

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image: CRISPR Corrects RNA-based Disease Defects

CRISPR Corrects RNA-based Disease Defects

By Kerry Grens | August 10, 2017

In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.

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image: Final Nail Hammered into NgAgo Coffin

Final Nail Hammered into NgAgo Coffin

By Kerry Grens | August 3, 2017

The paper describing the gene-editing method is retracted.

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image: Scientists Destroy Entire Chromosome with CRISPR

Scientists Destroy Entire Chromosome with CRISPR

By Kerry Grens | August 1, 2017

Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.

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image: Scientists Edit Viable Human Embryos in U.S.

Scientists Edit Viable Human Embryos in U.S.

By Kerry Grens | July 27, 2017

The embryos, whose genes were altered by CRISPR, were not intended for implantation. 

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