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tag funding evolution nih cancer clinical trials

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Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
EXCLUSIVE
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Clinical Trial Registry Errors Undermine Transparency
Catherine Offord | Aug 2, 2022 | 10 min read
A lack of comprehension among some researchers about how to use ClinicalTrials.gov may be hindering public access to trial information and holding up drug study results, an investigation by The Scientist finds.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Adaptive Evolution
Alla Katsnelson | Aug 1, 2009 | 7 min read
By Alla Katsnelson Adaptive Evolution A once-rare type of clinical trial that violates one of the sacred tenets of trial design is taking off, but is it worth the risk? Doriano Solinas When researchers at Pfizer first began a Phase 2 trial of an acute stroke therapy in 2000, they decided to take a novel approach. The study—called the ASTIN trial—would determine the drug’s optimal dose not with three or four diffe
Breaking Barriers to Participation in Cancer Clinical Trials
Robert Finn | Feb 20, 2000 | 6 min read
This issue of The Scientist chronicles many promising areas of cancer research, comprising a wide range of approaches to the treatment and prevention of our second-leading cause of death. But before any of these disparate approaches can begin to affect the rate of cancer mortality, they must pass through the bottleneck of human clinical trials. The pace of new ideas through the clinical trial process can seem maddeningly slow to patients and researchers alike. It takes far too long to get safe
Human Clinical Trials Begin For Cervical Cancer Vaccines
Steve Bunk | Oct 26, 1997 | 6 min read
Efforts are under way to develop a vaccine against one of the world's deadliest illnesses, cervical cancer. Along with a number of university research laboratories, at least a half-dozen biotechnology and pharmaceutical companies are beginning clinical trials or are in preclinical development of such drugs. Efficacy in humans remains to be firmly established, but if the vaccines progress to later-phase trials, challenging jobs for immunologists, microbiologists, and biochemists will multiply. "
Cancer Researchers Use Evolution to Target Drug Resistance
Catherine Offord | Apr 1, 2020 | 10+ min read
New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018 | 2 min read
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.
Updated July 9
Track COVID-19 Vaccines Advancing Through Clinical Trials
The Scientist | Apr 7, 2020 | 10+ min read
Find the latest updates in this one-stop resource, including efficacy data and side effects of approved shots, as well as progress on new candidates entering human studies.

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