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Illustration of light blue neurons with white amyloid plaques accumulating on their axons.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial

The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.

The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.

clinical trials, neuroscience

Woman holding a glass of water in one hand and pill in the other
Daily Multivitamin May Slow Cognitive Decline in Seniors
Andy Carstens | Sep 14, 2022 | 2 min read
Researchers caution that it’s too soon to recommend supplements based on the results of a new study.
A 3D rendering of a neuron
Independent FDA Advisory Panel Recommends Approving ALS Drug
Amanda Heidt | Sep 8, 2022 | 4 min read
The group’s 7-2 ruling in favor of the therapeutic represents a shift from previous deliberations, in which data on its effectiveness was deemed insufficient.
Precision Medicine-Based Biomarkers for Traumatic Brain Injury
Precision Medicine-Based Biomarkers for Traumatic Brain Injury 
The Scientist | 1 min read
In this webinar, Dr. Kevin Wang will discuss a precision medicine approach for treating traumatic brain injury which uses phenotype biomarkers to monitor disease course and develop novel therapies.
A conceptual 3D illustration of motor neurons degrading
Canada Approves Experimental ALS Therapy
Andy Carstens | Jun 14, 2022 | 3 min read
The country’s provisional go-ahead could increase pressure already being exerted on the US Food and Drug Administration to approve the therapy.
3D illustration showing neurons inside the brain
Experimental Pill to Treat Parkinson’s Is Safe, Trial Finds
Andy Carstens | Jun 10, 2022 | 2 min read
Testing in animals and lab-grown cells suggests the experimental drug could enhance the function of lysosomes within cells.
illustration of a brain divided into 4 puzzle pieces
Why Autism Therapies Have an Evidence Problem
Rachel Zamzow | Apr 14, 2022 | 7 min read
Some experts argue that better trials are needed before putting interventions into practice.
Illustration of neurons in white with myelin in blue
Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells
Jef Akst | Oct 12, 2021 | 2 min read
Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear.
An artistic rendering of blue neurons against a white background
Participant’s Diagnosis Halts Gene Therapy Clinical Trial
Amanda Heidt | Aug 12, 2021 | 3 min read
The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.
a drawing of black goggles receiving a beam of light than is then transmitted to an eyeball. from the retina there is a zoom-in of blue and purple cells and purple viruses
Blind Patient Recovers Partial Vision with Optogenetics
Alejandra Manjarrez, PhD | May 24, 2021 | 4 min read
After receiving an intraocular injection of the gene for a light-sensitive protein, a 58-year-old man diagnosed with the neurodegenerative eye disease retinitis pigmentosa was able to locate objects on a table using engineered goggles.
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Lisa Winter | Mar 16, 2021 | 2 min read
Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
an illustration of a person's head with the thalamus highlighted
Brain Stimulation Tested to Awaken Coma Patients
Shawna Williams | Feb 5, 2021 | 4 min read
Two out of three people who received noninvasive ultrasound appear to have gained some level of consciousness, according to preliminary trial results.
2020 in Scientists’ Own Words
Abby Olena, PhD | Dec 23, 2020 | 5 min read
The world was rocked by the COVID-19 pandemic this year, but researchers rose to all manner of challenges.
Michelle Gray Tracks Huntington’s in Different Brain Cells
Amanda Heidt | Oct 1, 2020 | 3 min read
The University of Alabama at Birmingham neuroscientist aims to determine which cells are most important in prompting the disease’s initiation and progression.
New Drug Combo for ALS Slows Decline in Small Clinical Study
Jef Akst | Sep 3, 2020 | 3 min read
After six months, patients with fast-progressing amyotrophic lateral sclerosis who had received the experimental treatment had less loss of function than those who received a placebo.
Interactive: Biomarkers in Blood Provide a Window into the Brain
Shawna Williams | Dec 1, 2019 | 1 min read
A look at some of the circulating molecules that may indicate various Alzheimer’s pathologies and serve as the bases of noninvasive tests for the disease.
The Hunt for a Blood Test for Alzheimer’s Disease
Shawna Williams | Dec 1, 2019 | 10 min read
Researchers hope circulating biomarkers will enable earlier detection and better monitoring of the neurodegenerative disorder—and perhaps help usher in new treatments.
Pelizaeus-Merzbacher disease neural stem cell transplantation
Neural Stem Cell Transplantation Crawls Toward the Clinic
Ashley P. Taylor | Oct 29, 2019 | 9 min read
Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.
Drug Approval Could Boost Research on Marijuana Treatment for Autism
Jessica Wright | Aug 17, 2018 | 4 min read
Epidiolex, a cannabis-derived medicine for epilepsy, will prompt federal regulatory changes that could crack open access to study the plant.
Ultrasound Opens Blood-Brain Barrier in Alzheimer’s Patients
Ashley Yeager | Jul 26, 2018 | 2 min read
A Phase 1 clinical trial shows the noninvasive technique is safe and could aid in the delivery treatments to the brain.
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