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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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image: Equivocal Findings of Alzheimer’s Trial Using Young Blood

Equivocal Findings of Alzheimer’s Trial Using Young Blood

By | November 6, 2017

A team of Stanford University researchers say that administering young people’s blood plasma to Alzheimer’s patients could improve cognitive function, but the results have been criticized.

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If approved, patisiran will be the first RNAi therapeutic on the market. 

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image: FDA Goes After Two Stem Cell Clinics

FDA Goes After Two Stem Cell Clinics

By | August 29, 2017

The agency raided one that was using a stem cell-smallpox vaccine combo, and sent a warning to another to obey best practices.

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image: Right-to-Try Bill Passes the Senate

Right-to-Try Bill Passes the Senate

By | August 4, 2017

The legislation removes restrictions for seriously ill patients to access experimental treatments that have not received FDA approval.

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In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse. 

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A new screening tool flags dozens of papers with potential errors.

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The publicly available database found nearly a third of samples included mutations targeted by either approved drugs or therapies in clinical trials. 

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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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image: DNA-Based Zika Vaccine Reaches Phase 2

DNA-Based Zika Vaccine Reaches Phase 2

By | April 4, 2017

An NIAID-sponsored clinical trial advances beyond safety testing.

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  4. Research Links Gut Health to Neurodegeneration
    The Nutshell Research Links Gut Health to Neurodegeneration

    Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

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