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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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image: Equivocal Findings of Alzheimer’s Trial Using Young Blood

Equivocal Findings of Alzheimer’s Trial Using Young Blood

By | November 6, 2017

A team of Stanford University researchers say that administering young people’s blood plasma to Alzheimer’s patients could improve cognitive function, but the results have been criticized.

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If approved, patisiran will be the first RNAi therapeutic on the market. 

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image: FDA Goes After Two Stem Cell Clinics

FDA Goes After Two Stem Cell Clinics

By | August 29, 2017

The agency raided one that was using a stem cell-smallpox vaccine combo, and sent a warning to another to obey best practices.

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image: Right-to-Try Bill Passes the Senate

Right-to-Try Bill Passes the Senate

By | August 4, 2017

The legislation removes restrictions for seriously ill patients to access experimental treatments that have not received FDA approval.

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In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse. 

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A new screening tool flags dozens of papers with potential errors.

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The publicly available database found nearly a third of samples included mutations targeted by either approved drugs or therapies in clinical trials. 

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image: Cell Lines Gain Cancer-Related Mutations

Cell Lines Gain Cancer-Related Mutations

By | April 27, 2017

A screen of human embryonic stem cell lines finds several that accumulated changes in the gene TP53, including aberrations commonly seen in cancer.

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