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image: New Ovarian Cancer Vaccine Shows Promise

New Ovarian Cancer Vaccine Shows Promise

By Catherine Offord | April 12, 2018

A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.

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Applications for Phase 1 and 2 human studies in Germany frequently lack sufficient information about an intervention’s efficacy in animal experiments, according to a new study.  

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image: Recipients of Experimental Herpes Vaccine File Lawsuit

Recipients of Experimental Herpes Vaccine File Lawsuit

By Catherine Offord | March 15, 2018

The suit claims that Rational Vaccines, the company of recently deceased researcher William Halford, violated US and international laws when it carried out the procedure.

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More than 3,500 scientists had signed an open letter to NIH Director Francis Collins opposing the rules change.

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Both higher education and industry associations were advocating for a later implementation date for the Common Rule, which governs human studies.

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image: CRISPR Trial for Cancer Patients Proposed

CRISPR Trial for Cancer Patients Proposed

By Katarina Zimmer | January 19, 2018

US researchers could become the first outside China to use the gene-editing technique in the clinic. 

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The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

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image: New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

New CAR T-Cell Therapy Shows Promise in Trial for Leukemia

By Katarina Zimmer | November 21, 2017

The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 

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image: Man Receives First In Vivo Gene-Editing Therapy

Man Receives First In Vivo Gene-Editing Therapy

By Kerry Grens | November 15, 2017

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

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image: Equivocal Findings of Alzheimer’s Trial Using Young Blood

Equivocal Findings of Alzheimer’s Trial Using Young Blood

By Catherine Offord | November 6, 2017

A team of Stanford University researchers say that administering young people’s blood plasma to Alzheimer’s patients could improve cognitive function, but the results have been criticized.

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