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Subjects
genetics & genomics, cancer
genetics & genomics, cancer
Some Human Cancers Exhibit Low-grade Inflammation
Alison F. Takemura
| Oct 1, 2016
| 2 min read
NSAIDs reduce this "parainflammation," hinting at how they help lower cancer risk.
Techniques for Assessing Genomic Copy Number Variations
Sarah C.P. Williams
| Oct 1, 2016
| 8 min read
As the importance of genomic copy number variations for health and disease becomes clearer, researchers are creating new ways to detect these changes in the genome.
Tasmanian Devils Developing Resistance to Transmissible Cancer
Abby Olena, PhD
| Aug 30, 2016
| 2 min read
The marsupials’ genomes show evidence of a rapid evolutionary response to selection imposed by devil facial tumor disease.
Transmissible Cancers Plague Mollusks
Anna Azvolinsky
| Jun 22, 2016
| 3 min read
Researchers identify three new examples of infectious cancers affecting these invertebrates.
Screening with CRISPR
Kelly Rae Chi
| Jun 1, 2016
| 7 min read
Ever-improving CRISPR-based tools are already ripe for large-scale genetic screens.
AACR Q&A: Angelika Amon
The Scientist
| Apr 19, 2016
| 3 min read
The aneuploidy expert shares what she has learned at the American Association for Cancer Research annual meeting.
A Tree Takes Root
Ashley P. Taylor
| Apr 1, 2016
| 4 min read
Four apparently unrelated individuals share a common ancestor from whom they inherited a rare mutation that predisposed them to the cancer they share.
Pulling It All Together
Kate Yandell
| Apr 1, 2016
| 9 min read
Systems-biology approaches offer new strategies for finding hard-to-identify drug targets for cancer.
Death in the Dust
The Scientist
| Mar 31, 2016
| 1 min read
Follow Michele Carbone as he tracks down the genetic and environmental drivers of mesothelioma and other cancers.
Mutations Not Tied to Metastasis
Kerry Grens
| Feb 25, 2016
| 3 min read
Clinical cases link immune changes to a cancer’s spread through the body, but find no role for so-called “driver” mutations.
Managing Methylation
Karen Zusi
| Jan 1, 2016
| 2 min read
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Telomerase Overdrive
Ashley P. Taylor
| Jan 1, 2016
| 2 min read
Two mutations in a gene involved in telomere extension reverse the gene’s epigenetic silencing.
Direct-to-Consumer Liquid Biopsy
Kerry Grens
| Sep 13, 2015
| 2 min read
Some doctors advise shoppers to be skeptical of a newly marketed cancer diagnostic.
Toward Blood-based Cancer Detection
Jyoti Madhusoodanan
| Jul 7, 2015
| 4 min read
Circulating tumor cells, exosomes, and DNA can improve the diagnosis of many cancers. But are liquid biopsies ready for prime time?
Time Bungles Precision Medicine
Kerry Grens
| Apr 20, 2015
| 2 min read
Personalized pancreatic cancer therapies based on tumor genomics may take too long to prepare to be helpful, according to a small clinical trial.
Cancer Sequencing Controls
Ruth Williams
| Apr 15, 2015
| 3 min read
Comparing a patient’s tumor DNA sequence with that of her normal tissue can improve researchers’ identification of disease-associated mutations.
Clam Cancer Rips Along Atlantic Coast
Jyoti Madhusoodanan
| Apr 9, 2015
| 3 min read
A leukemia that’s killing far-flung populations of softshell clams may be contagious.
Setbacks and Great Leaps
Sue Armstrong
| Apr 1, 2015
| 3 min read
The tale of
p53
, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
The Challenges of Precision
Adam Marcus
| Apr 1, 2015
| 3 min read
Researchers face roadblocks to treating an individual patient’s cancer as a unique disease.
Cancer Kismet
Jenny Rood
| Apr 1, 2015
| 4 min read
Fate mapping allows researchers to follow cancer progression from its cell type of origin.
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