immunology, disease & medicine

With her husband, she studied allergic reactions and identified antibodies that set off itching, wheezing, and rashes.

Quieting immune attacks against pathogens and even providing nutrients to the invaders could improve health, according to a new line of research.

Antigens originating from the microbiome may trigger an autoimmune response.

Symbiotic bacteria, metabolism, and stress pathways can all help animals tolerate, rather than succumb, to disease.

Tweaking the genomes of two phages and combining them with a third phage helped to clear a persistent Mycobacterium infection in the patient.

Although the oral treatment seems to work, an analysis of the results from 12 clinical trials finds kids who got an immunotherapy have a greater rate of serious reactions.

An early-stage clinical study finds that none of the 25 patients treated developed neurotoxicity or cytokine release syndrome, common hazards of the cancer immunotherapy.

Researchers report they’ve found a way to restore immune function in infants with one form of “bubble boy disease.”

After a severe case of flu, mice have chemosensory cells in their lungs, a place where they don’t normally occur.

The technology has wowed the field by all but obliterating some patients’ blood cancers, but solid malignancies present new challenges.

Tumor accessibility, heterogeneity, and microenvironment vary between the two classes of malignancies.

T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.

The “London patient” may represent the second person cured of the infection by a cell transplant.

High salt concentrations are present in the affected skin of people with atopic dermatitis and promote the differentiation of the T helper cells involved in the development of allergic diseases.

Mice exposed to heat wave temperatures ate less and showed weakened immune responses to the virus.

Immune cells in the mouse gut help recognize damaging compounds and prompt intestinal stem cells to repair DNA.

Researchers find that it’s not just high-risk genes, but how children’s bodies respond to their own intestinal microbiota that relates to future diagnoses of type 1 diabetes.

An enzyme of the bacteria Porphyromonas gingivalis has been found in the brains of patients with the disorder, and causes neurodegeneration in mice.

The head of the National Institute of Arthritis and Musculoskeletal and Skin Diseases was a leader in the study of skin-based immunology.

A study finds the effect is dose-dependent, with each additional pet further lowering the odds of developing allergies.