ADVERTISEMENT
ADVERTISEMENT

cancer, genetics

Illustration of two weaving proteins 
Fusion with Spider Silk Increases Anticancer Protein’s Stability
Dan Robitzski | Jul 5, 2022 | 2 min read
Scientists found that combining the notoriously flimsy anticancer protein p53 with a domain from a spider silk protein resulted in a more stable hybrid that’s more potent and easier for cells to synthesize.
3D rendering of a scanning electron micrograph of pink malignant cancer cells against a black background
Cancers Ramp Up Overall mRNA Expression as They Progress
Dan Robitzski | Jun 14, 2022 | 4 min read
A technique for quantifying tumor mRNA production from messy tissue sample data uncovers an unexpected correlation between it and disease stage in 15 cancer types.
Understanding Cancer Evolution Through the Lens of Single Cell Genomics
Understanding Cancer Evolution Through the Lens of Single Cell Genomics
The Scientist | 1 min read
Nicholas Navin and Lars Velten discuss sampling, sequencing, and tracing single cells to study how cancer cells adapt to various environments.
multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Illustration of light blue speckled DNA helix on a dark background
Study Nearly Doubles Known Cancer-Linked Mutational Signatures
Jef Akst | Apr 22, 2022 | 2 min read
Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.
logo
DNA Unlocked - A Special 3-Part Q&A Series
The Scientist Creative Services Team in collaboration with Amgen | 1 min read
Dive deeper into the DNA Unlocked podcasts
Abstract Genetics Disease stock photo
Bridging Disciplines to Study CRISPR-Induced Chromosome Destabilization
Aparna Nathan, PhD | Apr 8, 2022 | 4 min read
A collaboration between friends led to a cautionary finding about CRISPR’s effect on cells.
Female reproductive System Anatomy stock photo
Cells in the Ovary are Responsive Shape-Shifters
Roni Dengler, PhD | Apr 8, 2022 | 3 min read
Rounds of trial-and-error exploring the layer of cells covering the ovary leave open questions about stem cells that are associated with ovarian cancer.
Technique Talk: Single Cell Sequencing Sample Preparation for Oncology Research
The Scientist Creative Services Team in collaboration with 10x Genomics | 1 min read
In this workshop, learn tips and tricks for preparing cancer tissue samples for a variety of single cell applications.
Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
Samuel F. Bakhoum | Mar 1, 2022 | 10+ min read
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022 | 2 min read
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
Surveillance Gaps: How Cancer Arises
The Scientist | 1 min read
Surveillance Gaps: How Cancer Arises
chemical visualization of a G-quadruplex
Strange DNA Structures Linked to Cancer
Sophie Fessl, PhD | Jan 19, 2022 | 3 min read
A study reveals a connection between the loss of enzymes responsible for removing methyl groups from DNA, nucleic acid knots, and cancer development in mice.
man standing in front of gene sequencing machines
Q&A: Nearly Every Single Human Gene Can Be Linked to Cancer
Dan Robitzski | Oct 29, 2021 | 6 min read
The Scientist spoke with University of Liverpool aging and longevity researcher João Pedro de Magalhães about how human biases can influence scientific priorities and outcomes in genetics.
Technique Talk: Supporting Organoid Growth in 3D Cell Culture
The Scientist Creative Services Team in collaboration with Bio-Techne | 1 min read
In this workshop, you will learn how to optimally culture organoids and support their growth after genetic manipulation.
visualization of p53 protein interacting with its inhibitors MDM2 and MDMX
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
Marcus A. Banks | Jul 29, 2021 | 4 min read
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
streaks of blue and green from a fluorescent chromosome mapping technique
Optical Genome Mapping Works Well in Detecting Cancer Risk
Marcus A. Banks | Jul 22, 2021 | 3 min read
The relatively new technique for visually detecting chromosomal variants associated with disease risk performs at least as well as more established techniques in two recent studies.
A Little Help From My Friends: Lessons Learned From Microbiome Metagenomics
The Scientist | 1 min read
Heather Jordan and Jennifer Wargo will discuss how metagenomics studies help uncover new and medically relevant functions of the human microbiome.
A tasmanian devil with its nose in the air
Deadly Facial Tumors Spur Tasmanian Devil Evolution: Study
Christie Wilcox, PhD | Jun 16, 2021 | 6 min read
The largest study to date of the animals’ genetics provides robust evidence that they are adapting to survive a highly lethal, contagious cancer scientists feared would cause their extinction.
clear blood draw tubes with peach-colored caps and white labels with a red banner that has a DNA double helix icon and the word text. inside the tubes is a conceptual drawing of a DNA double helix in white
FDA-Led Consortium Details Improvements Needed in Liquid Biopsies
Marcus A. Banks | May 19, 2021 | 4 min read
In the largest effort to date to standardize performance metrics of the cancer diagnostic across products, researchers say the products can likely detect advanced tumors reliably, but early-stage malignancies would remain a challenge.
ADVERTISEMENT