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tag antibiotic resistance genetics genomics infectious disease immunology

3D illustration of greenish-brown rod-shaped bacteria.
A Novel Molecule to Tackle Drug-Resistant Bugs
Aparna Nathan, PhD | Feb 12, 2024 | 4 min read
A new antibiotic is the first to block a critical transport mechanism in drug-resistant bacteria.
The Evolution of Bats’ Super Immunity
Niki Spahich, PhD | Jan 10, 2024 | 4 min read
Researchers generated complete genomes of two important bat species and explored their immune- and cancer-related genes.
A bat flying in a dark cave
Turning on the Bat Signal
Hannah Thomasy, PhD | Mar 15, 2024 | 10+ min read
Scientists around the world investigate how bat immune systems cope with viral attacks and how this information could be used to keep humans safe.
bacteria and DNA molecules on a purple background.
Engineering the Microbiome: CRISPR Leads the Way
Mariella Bodemeier Loayza Careaga, PhD | Mar 15, 2024 | 10+ min read
Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.
Researchers use bacterial whole genome sequencing to compare the phylogenetic relationship between environmental and clinical samples.
Aquatic Bacteria Reveal a Common Genetic Link to a Deadly Human Pathogen
Iris Kulbatski, PhD | Mar 7, 2022 | 5 min read
Researchers use genetic clues to track the spread of antibiotic resistant bacteria from the environment to patients.
Eytan Stibbe wears a headset and a blue shirt while surrounded by computers and other equipment on the International Space Station.
Whenever, Wherever: Taking DNA Amplification Outside the Lab
Hannah Thomasy, PhD | Dec 4, 2023 | 10 min read
Recombinase polymerase amplification lets researchers rapidly replicate DNA in the clinic, in the field, or even in the International Space Station.
Stalking Infectious Disease
Eugene Russo | Jun 11, 2000 | 8 min read
Graphic: Cathleen Heard Law enforcement officials routinely use DNA fingerprinting as a tool to get the guilty punished. Defense lawyers often rely on the same tool to free the innocent. Though their labs may be less dramatic settings than criminal courtrooms, life science researchers also use DNA fingerprinting, but rather than capturing criminals, their goal is to keep tabs on a different sort of culprit: infectious disease. The technology has revolutionized the way diseases are tracked and th
Genomic Strategies Target Bacteria
Billy Goodman | May 1, 2000 | 6 min read
Bacteria are winning, and infectious disease doctors are worried. Disease-causing microbes are increasingly able to defeat the best antimicrobial drugs available. No "superbug" has yet emerged, resistant to all antibiotics and therefore untreatable. But that day may not be too far off. "There's increasing panic among infectious disease specialists,'' admits Jonathan Blum, a clinician and researcher at Harvard Medical School. Particularly worrisome to those specialists is a strain k
Genetically Modified Viral Cocktail Treats Deadly Bacteria in Teen
Ashley Yeager | May 8, 2019 | 2 min read
Tweaking the genomes of two phages and combining them with a third phage helped to clear a persistent Mycobacterium infection in the patient.
Targeting Antibiotic-Resistant Bacteria with CRISPR and Phages
Anna Azvolinsky | May 18, 2015 | 3 min read
Researchers develop a CRISPR-based, two-phage system that sensitizes resistant bacteria to antibiotics and selectively kills any remaining drug-resistant bugs. 

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