genetics, epigenetics, genetics & genomics, cell & molecular biology

By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.

Weill Cornell Medicine geneticist Christopher Mason speaks with The Scientist about a bolus of new work on the physiological, cellular, and molecular effects of leaving Earth.

Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.

Methylation on adenine bases is involved in the dampening of gene expression in mammalian cells, according to a study.

A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.

After spending more than a decade developing tools to study patterns in gene sequences, bioinformaticians are now working on programs to analyze epigenomics data.

Meet Wolf Reik, August Profilee and Babraham Institute director of research.

An epigenetic variant of cytosine is stable in the genomes of living mice, suggesting a possible expansion of the DNA alphabet.

Diverse mammals, including humans, have been found to carry distinct genomes in their cells. What does such genetic chimerism mean for health and disease?