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tag evolution vaccine genetics genomics microbiology

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Keeping Pace With SARS-CoV-2 Evolution
The Scientist Creative Services Team in collaboration with Thermo Fisher Scientific | Sep 29, 2021 | 1 min read
Eugene Koonin and Eric Niederkofler discuss novel technologies to improve viral mutation surveillance.
an illustration of the sars-cov-2 spike protein in purple tethered to the viral membrane in dark gray
Spike Protein Deletions Linked to COVID-19 Surges: Preprint
Alejandra Manjarrez, PhD | Jun 15, 2021 | 4 min read
Researchers find that surges in COVID-19 case numbers are associated with deletions in the SARS-CoV-2 genome in an antigenic site of the spike protein. Some of these mutations are present in vaccine breakthrough infections or reinfections.
An illustration of green bacteria floating above neutral-colored intestinal villi
The Inside Guide: The Gut Microbiome’s Role in Host Evolution
Catherine Offord | Jul 1, 2021 | 10+ min read
Bacteria that live in the digestive tracts of animals may influence the adaptive trajectories of their hosts.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
a veterinarian in a white hazmat suit holding a small pig
The Long Journey to Resolve the Origins of a Previous Pandemic
Martha Nelson | Sep 2, 2021 | 10+ min read
Dozens of researchers, including myself, worked for years to uncover that swine flu had leapt to humans from a pig in Mexico in 2009. We learned a lot about influenza evolution, pig farming, and outbreak risk along the way.
Illustration of a targeted virus over a world map
The Hunt for a Pandemic’s Origins
Martha Nelson | Jan 4, 2022 | 10+ min read
Dozens of researchers, including myself, worked for years to uncover that swine flu had leapt to humans from a pig in Mexico in 2009. We learned a lot about influenza evolution, pig farming, and outbreak risk along the way.
Special report
501Y.V2 b.1.1.7 B.1.351 coronavirus COVID-19 e484k epidemiology genetics & genomics k417n micro n501y news feature p.1 pandemic SARS-CoV-2 virology variants
A Guide to Emerging SARS-CoV-2 Variants
Katarina Zimmer | Jan 26, 2021 | 10 min read
Scientists across the world are closely tracking the spread of mutations in the coronavirus and investigating whether they could render current vaccines less effective.
Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018 | 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  
The Pangenome: Are Single Reference Genomes Dead?
Catherine Offord | Dec 1, 2016 | 10+ min read
Researchers are abandoning the concept of a list of genes sequenced from a single individual, instead aiming for a way to describe all the genetic variation within a species.

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