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image: Archaea Family Tree Blossoms, Thanks to Genomics

Archaea Family Tree Blossoms, Thanks to Genomics

By Amber Dance | June 1, 2018

Identification of new archaea species elucidates the domain’s unique biology and sheds light on its relationship to eukaryotes.

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image: New Technologies Shed Light on Caveolae

New Technologies Shed Light on Caveolae

By Ben Nichols | June 1, 2018

The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.

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image: Predicting Future Zoonotic Disease Outbreaks

Predicting Future Zoonotic Disease Outbreaks

By Ashley Yeager | June 1, 2018

A step-by-step study of diseases that jump species gives subtle clues about future epidemics.

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When the O’Neills learned that their daughter had Sanfilippo syndrome, a devastating rare disease, they created a GoFundMe campaign that raised $2 million in less than a year.

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image: Exome Sequencing Helps Crack Rare Disease Diagnosis

Exome Sequencing Helps Crack Rare Disease Diagnosis

By Amanda B. Keener | May 1, 2018

Clinical analyses of patients’ gene sequences are helping to provide answers where none were available before.

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Crowdfunding can power investigations into diseases that would otherwise receive little attention.

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Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.

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image: Slow March Toward a Canavan Cure

Slow March Toward a Canavan Cure

By Ashley Yeager | May 1, 2018

Two decades after a successful crowdfunding campaign, some clinical trial patients have seen improvements—but there’s still no approved treatment for the disease.

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Though Calliope Joy’s disease is too far progressed to be treatable, her parents have helped other children with metachromatic leukodystrophy get access to an experimental therapy.

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image: Macrophages Play a Double Role in Cancer

Macrophages Play a Double Role in Cancer

By Amanda B. Keener | April 1, 2018

Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.

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