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image: Epigenetics—A Primer

Epigenetics—A Primer

By Stefan Kubicek | March 1, 2011

There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.

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image: Environmental Impact

Environmental Impact

By David Berreby | March 1, 2011

Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.

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image: Best Places to Work Postdocs, 2011

Best Places to Work Postdocs, 2011

By Cristina Luiggi | March 1, 2011

Setting up your own scientific laboratory is no easy task, but this year’s respondents are using their postdoc experiences to prepare for the challenge.

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image: Opening a Can of Worms

Opening a Can of Worms

By Bob Grant | February 1, 2011

A father’s determination to help his son resulted in an experimental treatment for autism that uses roundworms to modulate inflammatory immune responses. Can the worms be used to treat other diseases?

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image: Face to Face with the Emotional Brain

Face to Face with the Emotional Brain

By Ahmad R. Hariri & Paul J. Whalen | February 1, 2011

Amygdala responses to the facial signals of others predict both normal and abnormal emotional states. An understanding of the brain chemistry underlying these responses will lead to new strategies for treating and predicting psychopathology.

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image: The Genes of Parkinson’s Disease

The Genes of Parkinson’s Disease

By Bobby Thomas and M. Flint Beal | February 1, 2011

The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.

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image: Mining Bacterial Small Molecules

Mining Bacterial Small Molecules

By L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | January 1, 2011

As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.

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From Simple To Complex

By Jef Akst | January 1, 2011

The switch from single-celled organisms to ones made up of many cells has evolved independently more than two dozen times. What can this transition teach us about the origin of complex organisms such as animals and plants?

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image: The Coming Health Crisis

The Coming Health Crisis

By Samuel S. Myers and Aaron Bernstein | January 1, 2011

Indirect effects of global climate change threaten the health of hundreds of millions of people. The very uncertainty that shrouds this issue must serve as an organizing principle for adaptation to its ill effects.

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Mafia Wars

By Jef Akst | June 1, 2010

An increasing amount of data is showing that the cellular battle between pathogens and hosts needs much more than a simple military metaphor to describe it—think undercover infiltration, front organizations, and forced suicide.

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