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image: Do Pathogens Gain Virulence as Hosts Become More Resistant?

Do Pathogens Gain Virulence as Hosts Become More Resistant?

By Andrew F. Read and Peter J. Kerr | October 1, 2017

Emerging infections provide clues about how pathogens might evolve when farm animals are protected from infection.

1 Comment

image: How Cancers Evolve Drug Resistance

How Cancers Evolve Drug Resistance

By Anna Azvolinsky | April 1, 2017

Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By Stephen P. Schoenberger and Ezra Cohen | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

1 Comment

image: May the Force Be with You

May the Force Be with You

By Ning Wang | February 1, 2017

The dissection of how cells sense and propagate physical forces is leading to exciting new tools and discoveries in mechanobiology and mechanomedicine.

5 Comments

image: A Different Way of Doing Things

A Different Way of Doing Things

By Kivanç Birsoy and David M. Sabatini | April 1, 2016

Cancer cells exhibit altered metabolic processes that may serve as promising targets for new therapies.

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image: Microbes Meet Cancer

Microbes Meet Cancer

By Kate Yandell | April 1, 2016

Understanding cancer’s relationship with the human microbiome could transform immune-modulating therapies.

4 Comments

image: The Forces of Cancer

The Forces of Cancer

By Lance L. Munn and Rakesh K. Jain | April 1, 2016

A tumor’s physical environment fuels its growth and causes treatment resistance.

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image: Breaking the Cancer-Obesity Link

Breaking the Cancer-Obesity Link

By Stephen D. Hursting, Ciara H. O’Flanagan, and Laura W. Bowers | November 1, 2015

Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?

2 Comments

image: Driven to Extinction

Driven to Extinction

By Jef Akst | July 1, 2015

The eradication of smallpox set the standard for the global elimination of a devastating infectious disease. Will the ongoing polio and guinea worm campaigns be as successful?

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image: Outbreak Observatory

Outbreak Observatory

By Jyoti Madhusoodanan | July 1, 2015

Increasingly precise remote-sensing data are helping researchers monitor and predict cases of infectious disease.

1 Comment

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