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image: Shooting Down Addiction

Shooting Down Addiction

By Thomas Kosten | June 1, 2011

A new breed of vaccines aims to wean users off cocaine.

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Power Failure

By Megan Scudellari | May 1, 2011

Does mitochondrial dysfunction lie at the heart of common, complex diseases like cancer and autism?

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image: The Movement of Goods Around the Cell

The Movement of Goods Around the Cell

By Patricia Bassereau and Bruno Goud | April 1, 2011

A biologist and a physicist collaborate on a decade-long exploration of the physical parameters of membrane traffic in eukaryotic cells.

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image: Taking Aim at Melanoma

Taking Aim at Melanoma

By Keith T. Flaherty | April 1, 2011

Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.

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image: An Aspirin for your Cancer?

An Aspirin for your Cancer?

By Giorgio Trinchieri | April 1, 2011

Can tumors—which can originate from, and often resemble, chronically inflamed tissue—be curtailed using familiar anti-inflammatory agents, without their side effects?

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image: Epigenetic Changes in Cancer

Epigenetic Changes in Cancer

By Manel Esteller | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.

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image: Epigenetics—A Primer

Epigenetics—A Primer

By Stefan Kubicek | March 1, 2011

There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.

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Environmental Impact

By David Berreby | March 1, 2011

Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.

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image: Opening a Can of Worms

Opening a Can of Worms

By Bob Grant | February 1, 2011

A father’s determination to help his son resulted in an experimental treatment for autism that uses roundworms to modulate inflammatory immune responses. Can the worms be used to treat other diseases?

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image: Face to Face with the Emotional Brain

Face to Face with the Emotional Brain

By Ahmad R. Hariri & Paul J. Whalen | February 1, 2011

Amygdala responses to the facial signals of others predict both normal and abnormal emotional states. An understanding of the brain chemistry underlying these responses will lead to new strategies for treating and predicting psychopathology.

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