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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: Advancing Techniques Reveal the Brain’s Impressive Diversity

Advancing Techniques Reveal the Brain’s Impressive Diversity

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

No two neurons are alike. What does that mean for brain function?

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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By Amanda B. Keener | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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image: Do Pathogens Gain Virulence as Hosts Become More Resistant?

Do Pathogens Gain Virulence as Hosts Become More Resistant?

By Andrew F. Read and Peter J. Kerr | October 1, 2017

Emerging infections provide clues about how pathogens might evolve when farm animals are protected from infection.

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image: Decoding the Tripping Brain

Decoding the Tripping Brain

By Diana Kwon | September 1, 2017

Scientists are beginning to unravel the mechanisms behind the therapeutic effects of psychedelic drugs.

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image: The Role of DNA Base Modifications

The Role of DNA Base Modifications

By Skirmantas Kriaucionis | September 1, 2017

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

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image: Your Body Is Teeming with Weed Receptors

Your Body Is Teeming with Weed Receptors

By Megan Scudellari | July 17, 2017

And the same endocannabinoid system that translates marijuana's buzz-inducing compounds into a high plays crucial roles in health and disease outside the brain.

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image: The Celiac Surge

The Celiac Surge

By Catherine Offord | June 1, 2017

A rapid increase in the global incidence of the condition has researchers scrambling to understand the causes of the trend, and cope with the consequences.

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image: How Cancers Evolve Drug Resistance

How Cancers Evolve Drug Resistance

By Anna Azvolinsky | April 1, 2017

Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.

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