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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By Stephen P. Schoenberger and Ezra Cohen | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

1 Comment

image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By Jyoti Madhusoodanan | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

1 Comment

image: RNA Interference Between Kingdoms

RNA Interference Between Kingdoms

By Kerry Grens | February 1, 2017

Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.

6 Comments

image: May the Force Be with You

May the Force Be with You

By Ning Wang | February 1, 2017

The dissection of how cells sense and propagate physical forces is leading to exciting new tools and discoveries in mechanobiology and mechanomedicine.

5 Comments

image: Repurposing Existing Drugs for New Indications

Repurposing Existing Drugs for New Indications

By Anna Azvolinsky | January 1, 2017

An entire industry has sprung up around resurrecting failed drugs and recycling existing compounds for novel indications.

1 Comment

image: Nuclear Pores Come into Sharper Focus

Nuclear Pores Come into Sharper Focus

By Daniel H. Lin and André Hoelz | December 1, 2016

Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.

1 Comment

image: Top 10 Innovations 2016

Top 10 Innovations 2016

By The Scientist Staff | December 1, 2016

This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.

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image: Viruses of the Human Body

Viruses of the Human Body

By Eric Delwart | November 1, 2016

Some of our resident viruses may be beneficial.

4 Comments

image: Immune System Maintains Brain Health

Immune System Maintains Brain Health

By Amanda B. Keener | November 1, 2016

Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.

3 Comments

image: Gene Editing: From Roots to Riches

Gene Editing: From Roots to Riches

By Amanda B. Keener | October 1, 2016

Advances in genetic manipulation have simplified the once daunting task of rewriting a gene.

2 Comments

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