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image: Wrestling with Recurrent Infections

Wrestling with Recurrent Infections

By Gayatri Vedantam and Glenn S. Tillotson | May 1, 2011

Clostridium difficile is evolving more robust toxicity, repeatedly attacking its victims, and driving the search for alternative therapies to fight the infection.

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image: The Movement of Goods Around the Cell

The Movement of Goods Around the Cell

By Patricia Bassereau and Bruno Goud | April 1, 2011

A biologist and a physicist collaborate on a decade-long exploration of the physical parameters of membrane traffic in eukaryotic cells.

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image: Taking Aim at Melanoma

Taking Aim at Melanoma

By Keith T. Flaherty | April 1, 2011

Understanding oncogenesis at the molecular level offers the prospect of tailoring treatments much more precisely for patients with advanced cases of this deadliest of skin cancers.

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image: An Aspirin for your Cancer?

An Aspirin for your Cancer?

By Giorgio Trinchieri | April 1, 2011

Can tumors—which can originate from, and often resemble, chronically inflamed tissue—be curtailed using familiar anti-inflammatory agents, without their side effects?

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image: Epigenetic Changes in Cancer

Epigenetic Changes in Cancer

By Manel Esteller | March 1, 2011

The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies.

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image: Environmental Impact

Environmental Impact

By David Berreby | March 1, 2011

Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.

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image: Face to Face with the Emotional Brain

Face to Face with the Emotional Brain

By Ahmad R. Hariri & Paul J. Whalen | February 1, 2011

Amygdala responses to the facial signals of others predict both normal and abnormal emotional states. An understanding of the brain chemistry underlying these responses will lead to new strategies for treating and predicting psychopathology.

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image: The Genes of Parkinson’s Disease

The Genes of Parkinson’s Disease

By Bobby Thomas and M. Flint Beal | February 1, 2011

The minority of Parkinson’s cases now known to have genetic origins are shedding light on the cellular mechanisms of all the rest, bringing researchers closer to a cause—and perhaps a cure.

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image: Mining Bacterial Small Molecules

Mining Bacterial Small Molecules

By L. Caetano M. Antunes, Julian E. Davies and B. Brett Finlay | January 1, 2011

As much as rainforests or deep-sea vents, the human gut holds rich stores of microbial chemicals that should be mined for their pharmacological potential.

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From Simple To Complex

By Jef Akst | January 1, 2011

The switch from single-celled organisms to ones made up of many cells has evolved independently more than two dozen times. What can this transition teach us about the origin of complex organisms such as animals and plants?

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