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The neuronal coverings that mediate synaptic changes are involved in everything from memory to psychiatric disorders, affecting autism, Alzheimer’s, and addiction.

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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By Mark R. Hutchinson | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: Getting Drugs Past the Blood-Brain Barrier

Getting Drugs Past the Blood-Brain Barrier

By Amanda B. Keener | November 1, 2017

To treat neurological disease, researchers develop techniques to bypass or trick the guardian of the central nervous system.

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image: Macrophages Are the Ultimate Multitaskers

Macrophages Are the Ultimate Multitaskers

By Claire Asher | October 1, 2017

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

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image: The Role of DNA Base Modifications

The Role of DNA Base Modifications

By Skirmantas Kriaucionis | September 1, 2017

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

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image: Uncovering Functions of Circular RNAs

Uncovering Functions of Circular RNAs

By Catherine Offord | July 17, 2017

Recent research has revealed many surprises about circular RNAs, from findings that they are translated in vivo to links between their expression and disease.

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image: Your Body Is Teeming with Weed Receptors

Your Body Is Teeming with Weed Receptors

By Megan Scudellari | July 17, 2017

And the same endocannabinoid system that translates marijuana's buzz-inducing compounds into a high plays crucial roles in health and disease outside the brain.

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image: Circadian Rhythms Influence Treatment Effects

Circadian Rhythms Influence Treatment Effects

By Jyoti Madhusoodanan | April 1, 2017

Across many diseases, taking medication at specific times of day may make the therapy more effective.

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