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image: Macrophages Play a Double Role in Cancer

Macrophages Play a Double Role in Cancer

By Amanda B. Keener | April 1, 2018

Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.

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Multidrug combinations lead to better results for cancer patients, but efficiently identifying them is proving difficult.

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image: Eat Yourself to Live: Autophagy’s Role in Health and Disease

Eat Yourself to Live: Autophagy’s Role in Health and Disease

By Vikramjit Lahiri and Daniel J. Klionsky | March 1, 2018

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

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image: Researchers Learn from Plant Viruses to Protect Crops

Researchers Learn from Plant Viruses to Protect Crops

By Claire Asher | February 1, 2018

Plants are locked in an ancient arms race with hostile viruses, but genome editing is giving crops the upper hand.

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image: Macrophages Are the Ultimate Multitaskers

Macrophages Are the Ultimate Multitaskers

By Claire Asher | October 1, 2017

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

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image: Do Microbes Trigger Alzheimer’s Disease?

Do Microbes Trigger Alzheimer’s Disease?

By Jill U. Adams | September 1, 2017

The once fringe idea is gaining traction among the scientific community.

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image: How Cancers Evolve Drug Resistance

How Cancers Evolve Drug Resistance

By Anna Azvolinsky | April 1, 2017

Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.

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image: Neoantigens Enable Personalized Cancer Immunotherapy

Neoantigens Enable Personalized Cancer Immunotherapy

By Stephen P. Schoenberger and Ezra Cohen | April 1, 2017

Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.

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image: May the Force Be with You

May the Force Be with You

By Ning Wang | February 1, 2017

The dissection of how cells sense and propagate physical forces is leading to exciting new tools and discoveries in mechanobiology and mechanomedicine.

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image: Repurposing Existing Drugs for New Indications

Repurposing Existing Drugs for New Indications

By Anna Azvolinsky | January 1, 2017

An entire industry has sprung up around resurrecting failed drugs and recycling existing compounds for novel indications.

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