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drug development, disease & medicine

Gilead Urged to Explore Remdesivir Relative as COVID-19 Drug
Catherine Offord | Aug 11, 2020 | 2 min read
Citizen advocates push the pharmaceutical company to examine a compound that has been used to treat certain coronavirus infections in cats.
Infographic: What is ME/CFS?
Katarina Zimmer | Aug 11, 2020 | 4 min read
The COVID-19 pandemic is sparking renewed efforts to study the underlying causes of this complex, debilitating disease, which might be triggered by the novel coronavirus.
Russia Approves World’s First Coronavirus Vaccine
Jef Akst | Aug 11, 2020 | 2 min read
Some researchers express skepticism given the lack of data about the vaccine’s safety and efficacy, and the country plans to vaccinate healthcare workers, teachers, and others even before testing is complete.
Alzheimer's Disease, Neurology, Influenza, Pneumonia, Vaccine, Pneumococcal, Immune System, Dementia
Flu and Pneumonia Vaccines Linked to Reduced Risk of Alzheimer’s
Amanda Heidt | Jul 27, 2020 | 3 min read
The authors propose that the shots might keep the immune system primed to battle diseases that would otherwise contribute to cognitive decline.
Activities Discovered for Some Inactive Drug Ingredients
Ruth Williams | Jul 23, 2020 | 4 min read
Screens of hundreds of drug excipients reveal that some can interact with biological targets, contradicting their FDA categorization as inert.
Special Report
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Seeking an Early COVID-19 Drug, Researchers Look to Interferons
Alakananda Dasgupta | Jul 20, 2020 | 9 min read
These antiviral proteins are produced by the body as a natural defense against viral infections and synthetic interferons might help prevent or treat the beginning stages of SARS-CoV-2 infection.
Opinion: Scientists in the US and China Collaborating on COVID-19
Jenny J. Lee and John P. Haupt | Jun 22, 2020 | 4 min read
Despite high-profile political tensions between the two countries, researchers in the US and China are working together now more than ever, according to our bibliometric study.
Remdesivir Shows Promise in Largest of Several Clinical Trials
Catherine Offord | Apr 30, 2020 | 3 min read
Gilead’s experimental antiviral drug shortened the average time it took COVID-19 patients to recover in a NIAID-sponsored trial. There was weak evidence that it also helped reduce deaths.
Opinion: Ethically Accessing Experimental Therapies for COVID-19
John D. Loike and Jennifer E. Miller | Apr 8, 2020 | 4 min read
In the midst of a pandemic, individual patients are not always the focus of the ethics discussions.
Updated July 9
Track COVID-19 Vaccines Advancing Through Clinical Trials
The Scientist | Apr 7, 2020 | 10+ min read
Find the latest updates in this one-stop resource, including efficacy data and side effects of approved shots, as well as progress on new candidates entering human studies.
Image of the Day: Defective Cilia
Amy Schleunes | Apr 7, 2020 | 1 min read
Super-resolution imaging identifies abnormalities in the hair-like protrusions on a cell’s surface and may help facilitate earlier detection of primary ciliary dyskinesia.
Infographic: Researchers Take Aim at Cancer Evolution
Catherine Offord | Apr 1, 2020 | 2 min read
Strategies to trick, manipulate, and direct the evolution of tumors
Bacteria as Living Microrobots to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 10+ min read
Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.
Cancer Researchers Use Evolution to Target Drug Resistance
Catherine Offord | Apr 1, 2020 | 10+ min read
New therapeutic approaches in oncology aim to manipulate or block cancer’s adaptation to treatment.
COVID-19 Vaccine Developers Gain Enhanced Access to Supercomputers
Lisa Winter | Mar 27, 2020 | 2 min read
Federal agencies, academic institutions, and industrial partners are joining forces to combat COVID-19 using artificial intelligence.
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Opinion: Stop Private Speculation in COVID-19 Research
Emiliano Brancaccio and Ugo Pagano | Mar 23, 2020 | 3 min read
We present an economic plan for a collective sharing of scientific knowledge on the pandemic.
Clinical Trial of COVID-19 Vaccine Begins in Seattle
Amy Schleunes | Mar 16, 2020 | 2 min read
The first volunteer will receive a shot of the synthetic RNA vaccine today.
Scientists Use Online Game to Research COVID-19 Treatment
Emma Yasinski | Mar 9, 2020 | 3 min read
The creativity of citizen scientists could help researchers design proteins that may be able to fight the SARS-CoV-2 virus.
abilify Aripiprazole autism side effects spectrum
How Aripiprazole’s Promise for Treating Autism Fell Short
Hannah Furfaro | Feb 27, 2020 | 10+ min read
Aripiprazole, marketed as Abilify, is widely thought to be safer than risperidone, the only other drug approved for use in autistic children. A decade’s worth of data suggests that is not true.
the torso and head of a man being 3-D printed
On the Road to 3-D Printed Organs
Emma Yasinski | Feb 26, 2020 | 6 min read
Researchers can print cells and biomaterials that make up human tissues, but there’s still a long way to go before fully functional organs can be made to order.
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