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image: New Technologies Shed Light on Caveolae

New Technologies Shed Light on Caveolae

By Ben Nichols | June 1, 2018

The functions of the cellular invaginations identified more than half a century ago are now beginning to be understood in detail.

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Government incentives, advances in technology, and an army of patient advocates have spun a successful market—but abuses of the system and exorbitant prices could cause a backlash.

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The neuronal coverings that mediate synaptic changes are involved in everything from memory to psychiatric disorders, affecting autism, Alzheimer’s, and addiction.

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Multidrug combinations lead to better results for cancer patients, but efficiently identifying them is proving difficult.

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Research into the biological basis of gender identity is in its infancy, but clues are beginning to emerge.

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image: Glial Ties to Persistent Pain

Glial Ties to Persistent Pain

By Mark R. Hutchinson | January 1, 2018

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

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image: Targeting Sodium Channels for Pain Relief

Targeting Sodium Channels for Pain Relief

By Catherine Offord | January 1, 2018

The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.

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image: Animal Analgesics

Animal Analgesics

By The Scientist Staff | January 1, 2018

A cornucopia of toxins in the animal kingdom could provide inspiration for novel painkillers, but so far, effective drugs have proven elusive.  

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image: Frog Skin Yields Potent Painkillers, but None Clinic Ready

Frog Skin Yields Potent Painkillers, but None Clinic Ready

By Shawna Williams | January 1, 2018

Decades after their discovery by bioprospectors, amphibian-derived analgesics continue to attract scientific attention.

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image: Mining Spider Toxins for Analgesic Clues

Mining Spider Toxins for Analgesic Clues

By Catherine Offord | January 1, 2018

Arachnids harbor a plentiful array of molecules that target mammalian pain receptors.

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