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When the O’Neills learned that their daughter had Sanfilippo syndrome, a devastating rare disease, they created a GoFundMe campaign that raised $2 million in less than a year.

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image: Exome Sequencing Helps Crack Rare Disease Diagnosis

Exome Sequencing Helps Crack Rare Disease Diagnosis

By Amanda B. Keener | May 1, 2018

Clinical analyses of patients’ gene sequences are helping to provide answers where none were available before.

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Crowdfunding can power investigations into diseases that would otherwise receive little attention.

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image: Slow March Toward a Canavan Cure

Slow March Toward a Canavan Cure

By Ashley Yeager | May 1, 2018

Two decades after a successful crowdfunding campaign, some clinical trial patients have seen improvements—but there’s still no approved treatment for the disease.

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image: Eat Yourself to Live: Autophagy’s Role in Health and Disease

Eat Yourself to Live: Autophagy’s Role in Health and Disease

By Vikramjit Lahiri and Daniel J. Klionsky | March 1, 2018

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

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image: Researchers Learn from Plant Viruses to Protect Crops

Researchers Learn from Plant Viruses to Protect Crops

By Claire Asher | February 1, 2018

Plants are locked in an ancient arms race with hostile viruses, but genome editing is giving crops the upper hand.

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New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

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image: Advancing Techniques Reveal the Brain’s Impressive Diversity

Advancing Techniques Reveal the Brain’s Impressive Diversity

By Sara B. Linker, Tracy A. Bedrosian, and Fred H. Gage | November 1, 2017

No two neurons are alike. What does that mean for brain function?

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image: Macrophages Are the Ultimate Multitaskers

Macrophages Are the Ultimate Multitaskers

By Claire Asher | October 1, 2017

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

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image: Do Microbes Trigger Alzheimer’s Disease?

Do Microbes Trigger Alzheimer’s Disease?

By Jill U. Adams | September 1, 2017

The once fringe idea is gaining traction among the scientific community.

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