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Out, Damned Mycoplasma!
Kelly Rae Chi | Dec 1, 2013 | 8 min read
Pointers for keeping your cell cultures free of mycoplasma contamination
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Using CRISPR to Edit Genes in Induced Pluripotent Stem Cells
Kelly Rae Chi | Sep 1, 2016 | 8 min read
Tips on how to surmount the challenges of working with CRISPR to manipulate genes in human stems cells to study their function in specific diseases or to correct genetic defects in patient cells.
PCR Primed To Spur Chain Of Applications
Holly Ahern | Jun 25, 1995 | 10+ min read
What would you do if your research interests revolved around obtaining DNA from a bacterium preserved for millions of years in the gut of a bee stuck in amber, matching up a murderer to crime- scene blood half a century old, or cloning genes from a 1,000- year-old mummy? Most scientists would first consider PCR--the polymerase chain reaction--as a technique for approaching problems such as these. With PCR, minute quantities of nucleic acids can be amplified millions of times into sufficient qua
2006 Life Science Industry Awards
Jeffrey M. Perkel and Ishani Ganguli | Apr 1, 2006 | 10+ min read
FEATURELSIA 2006 Our fourth annual event celebrates excellence in life science product development and services BY JEFFREY M. PERKEL AND ISHANI GANGULI It has been said that scientists stand on the shoulders of giants. Generally that refers to researchers' intellectual forebears, but it also is true of the life science industry - technology giants that provide the scientific community with the tools, equipment and
High Fidelity PCR: Enhancing the Accuracy of DNA Amplification
Shane Beck | Jan 4, 1998 | 10 min read
Date: January 5, 1998 Chart 1, Chart 2 n the beginning there was Taq. Actually, there were others before Taq. There were precursory polymerases, such as that from E. coli, that lost their enzymatic activities at elevated temperatures. This shortfall made thermal cycling a time-consuming chore, with the necessity of adding new polymerase after each cycle. Then came the thermostable polymerases such as Taq DNA polymerase, which was isolated from the thermophilic, aerobic bacterium Thermus aquat
The Zombie Literature
Bob Grant | May 1, 2016 | 10 min read
Retractions are on the rise. But reams of flawed research papers persist in the scientific literature. Is it time to change the way papers are published?
An illustration of flowers in the shape of the female reproductive tract
Uterus Transplants Hit the Clinic
Jef Akst | Aug 1, 2021 | 10+ min read
With human research trials resulting in dozens of successful deliveries in the US and abroad, doctors move toward offering the surgery clinically, while working to learn all they can about uterine and transplant biology from the still-rare procedure.
map of ukraine
Science Comes to a Halt in Ukraine, at Risk in Russia
Anna Azvolinsky | Mar 4, 2022 | 6 min read
The Russian invasion into Ukraine that began a week ago has forced Ukrainian scientists to abandon their labs and is putting research in Russia in peril.
New Products
The Scientist Staff | Feb 2, 1997 | 9 min read
The ABI PRISM 877 Integrated Thermal Cycler complements Perkin-Elmer Applied Biosystems' offerings for DNA sequencing and analysis, which include instrumentation, reagents, and data-management products. The 384-well thermal cycler is integrated with a robot capable of pipetting extremely low volumes necessary for both polymerase chain reaction (PCR) and sequencing reactions, enabling these operations to be carried out on a single platform. Users may choose to run preprogrammed protocols or c

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