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early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

epigenetics, disease & medicine, genetics & genomics

Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020 | 5 min read
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019 | 3 min read
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Ashley Yeager | Mar 21, 2019 | 6 min read
Certain populations have been historically underrepresented in genome sequencing studies, but the NIH, private clinics, and 23andMe and other companies are trying to fix that.
In Their Earliest Days, Embryos Record Their Environments
Kerry Grens | Oct 1, 2018 | 4 min read
Methylation patterns at so-called metastable epialleles in the genome stamp a memory into each of our cells.
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