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tag mutations science publishing dna methylation neuroscience

Epigenetic Changes Drive Cancer 
Rebecca Roberts, PhD | Nov 28, 2023 | 3 min read
An analysis of almost 700 different tumors revealed that DNA methylation drives tumorigenesis just like genetic mutations do. 
Surreal illustration of the mind, represented by a person-shaped iceberg. A scuba diver illuminates the dark side of the iceberg underwater with a flashlight.
Toward Better Biomarkers for Schizophrenia
Deanna MacNeil, PhD | Aug 7, 2023 | 3 min read
Researchers scratch the surface of schizophrenia susceptibility by uncovering DNA methylation differences in neonatal blood samples.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Nerve cell labelled with different colours
Psychedelics Slip Past Cell Membranes When Treating Depression
Alejandra Manjarrez, PhD | Feb 24, 2023 | 4 min read
The antidepressant properties of hallucinogenic drugs may stem from their ability to bind to intracellular serotonin receptors, a study suggests.
Histology of brain
Rare Autism-Linked Mutation Starves Growing Neurons of Essential Nutrients
Lauren Schenkman, Spectrum | Apr 18, 2023 | 4 min read
The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.
A mutated cell with a spiky membrane
Mutations in Autism-Linked Gene Cause Membrane Mischief
Holly Barker, PhD, Spectrum | Jan 26, 2023 | 4 min read
Inactivating TAOK1 prompts tentacle-like protrusions to form all over a neuron’s surface, revealing the gene’s role in molding the membrane.
Methylation Maestro
Anna Azvolinsky | Jan 1, 2017 | 9 min read
After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.
DNA Methylation Linked to Memory Loss
Sabrina Richards | Jul 2, 2012 | 3 min read
Scientists find that declining DNA methylation in mouse neurons may cause age-related memory deficits.
Illustration of a human and Neanderthal skull side by side.
Mutation Linked to Difference Between Human and Neanderthal Brains
Dan Robitzski | Sep 9, 2022 | 5 min read
A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.
Haydeh Payami is wearing a purple dress and an orange and pink scarf and standing in front of a whiteboard.
A Microbial Link to Parkinson’s Disease
Mariella Bodemeier Loayza Careaga, PhD | Dec 4, 2023 | 6 min read
Haydeh Payami helped uncover the genetic basis of Parkinson’s disease. Now, she hopes to find new ways to treat the disease by studying the gut microbiome.

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