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The image shows four different bones with varying degrees of osteoporosis.
A Molecular Switch for Bone Loss
Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 
A Molecular Switch for Bone Loss
A Molecular Switch for Bone Loss

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 

Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice. 

bone growth

Learn about hot topics in organoid research
Next-Level Organoids
The Scientist | Jul 22, 2022 | 1 min read
Researchers use organoid cultures in unique ways to study health and disease.
An artistic rendering of a dinosaur fleeing a wall of water
Cretaceous Meteor That Killed Most Life on Earth Hit in Spring
Amanda Heidt | Feb 24, 2022 | 5 min read
Researchers determined the season during which the meteor struck by studying the bones of fish excavated from a contentious field site.
Luis Alvarez Aims to Heal Wounds with Tissue-Regenerating “Paint”
Shawna Williams | Jul 13, 2020 | 3 min read
The bioactive coating tethers restorative proteins to implanted tissues and fosters new growth, animal studies suggest.
Bubbles for Broken Bones
Ruth Williams | Sep 1, 2017 | 3 min read
Ultrasound-stimulated microbubbles enable gene delivery to fix fractures.
Infographic: Ultrasound-Stimulated Microbubbles Fix Fractures
Ruth Williams | Aug 31, 2017 | 1 min read
The new technique helped pig tibias heal in just eight weeks.
Stem Cell Therapy In Utero
Kerry Grens | Oct 13, 2015 | 1 min read
An upcoming clinical trial aims to correct for a disease of fragile bones in affected babies before they are born.
Straighten Out
Kate Yandell | Jan 1, 2015 | 3 min read
Forces from bidirectional growth plates mechanically realign broken bones in infant mice.
Statins Stimulate Bone Growth?
Kate Yandell | Sep 17, 2014 | 3 min read
The cholesterol-lowering drugs could be used to treat people with two types of dwarfism, a study suggests.
A Bone-Deep Kinship
Jef Akst | Sep 1, 2013 | 3 min read
A Neanderthal rib fragment provides conclusive evidence that the ancient hominins were susceptible to a benign bone tumor of modern humans.
The Best of Experimental Biology
Edyta Zielinska | Apr 25, 2012 | 3 min read
From breast milk stem cells to bone repair, this year’s EB conference held a number of exciting advances that could one day be translated into therapies.
Suspected Effects of Vitamin D
Amy Maxmen | Mar 1, 2012 | 1 min read
Vitamin D has a variety of actions in the body. It binds to the vitamin D receptor (VDR), which then binds to the retinoid X receptor (RXR) and activates the expression of numerous genes. 
Vitamin D on Trial
Amy Maxmen | Mar 1, 2012 | 10+ min read
Prevention trials for vitamins and supplements are notoriously difficult, but some researchers aren’t giving up on finding proof that vitamin D helps ward off disease.
Skeleton Keys
Lewis Wolpert | May 14, 2011 | 3 min read
There are a surprising number of unknowns about how our limbs come to be symmetrical.
The World's Densest Bones
Kirsten Weir | Oct 1, 2006 | 3 min read
How a car accident led to an important genetic discovery
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