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tag limb development dna methylation mutations human evolution

Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
Illustration from the epigenetics and the genome infographic
Infographic: How Epigenetic Marks Can Change the Genome
Katarina Zimmer | Nov 1, 2022 | 2 min read
Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
A Long Line of LINEs
Kate Yandell | Sep 1, 2014 | 3 min read
Different mechanisms repress mobile DNA elements in human embryonic stem cells depending on the elements’ evolutionary ages.
Composite image showing genes radiating from tumor cells
Jumping Genes’ Role in Cancer
Diana Kwon | Mar 1, 2023 | 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
A close-up image of pale green seeds inside of a green capsule taken by a scanning electron microscope
Essential Genes Protected from Mutations
Dan Robitzski | Jan 25, 2022 | 6 min read
Epigenetic structures appear to reduce the rate of changes in genes essential for survival and reproduction, a study finds, challenging the notion that mutations are evenly distributed throughout the genome prior to selection.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017 | 10+ min read
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Methylation: Gene Expression at the Right Place and Right Time
Nadia Halim | Dec 5, 1999 | 7 min read
Courtesy of Richard Roberts, New England BiolabsModel methylation reaction: Cytosine nucleotide (red) is flipped out of the DNA double helix by a methyltransferase (white), so it can be methylated. The end product after the methyl group has been transferred to the DNA is pictured in green. A tenuous link between DNA methylation and development has existed for several years. Now findings substantiate the connection. Researchers have found the first human diseases caused by defects in the DNA meth
How to Calculate Mutation Rate for Evolutionary Biology
Amber Dance | Jul 1, 2018 | 6 min read
Four ways to study mutation rate, a crucial statistic in studies of evolution
Decoding Human Accelerated Regions
Katherine S. Pollard | Aug 1, 2016 | 10 min read
Do the portions of our genomes that set us apart from other animals hold the secret to human evolution?

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