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tag limb development stem cells dna methylation mutations neuroscience

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Three Autism-Linked Genes Converge on Tweaks to Cells’ Timing
Angie Voyles Askham, Spectrum | Feb 3, 2022 | 3 min read
The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism.
DNA Methylation Linked to Memory Loss
Sabrina Richards | Jul 2, 2012 | 3 min read
Scientists find that declining DNA methylation in mouse neurons may cause age-related memory deficits.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Researchers Engineer Epigenome Editors to Study How Gene Expression Affects Disease
Ashley Yeager | Jan 1, 2019 | 7 min read
Using CRISPR and other tools, scientists are modifying DNA methylation, histone marks, and other modifiers of gene expression to understand how they affect health and disease.
Integrating Multiple -Omics in Individual Cells
Sandeep Ravindran | Oct 1, 2018 | 8 min read
New techniques combine DNA, RNA, and protein information from single cells.
Infographic: Understanding Our Diverse Brain
Fred H. Gage, Tracy A. Bedrosian, and Sara B. Linker | Oct 31, 2017 | 2 min read
Recent advances in single-cell omics and other techniques are revealing variation at genomic, epigenomic, transcriptomic, and posttranscriptomic levels.
Embryonic stem lines unstable
Charles Choi(cqchoi@nasw.org) | Sep 5, 2005 | 3 min read
Genomic changes could render federally appointed lines unusable therapeutically, says Nature Genetics report
Pluripotent Until Needed
Beth Marie Mole | Apr 1, 2013 | 7 min read
Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.
Advancing Techniques Reveal the Brain’s Impressive Diversity
Sara B. Linker, Fred H. Gage, and Tracy A. Bedrosian | Nov 1, 2017 | 10+ min read
No two neurons are alike. What does that mean for brain function?
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019 | 10+ min read
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.

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