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tag science publishing dna methylation evolution

a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Ribosomal DNA Can Predict an Animal’s Age
Abby Olena, PhD | Feb 14, 2019 | 3 min read
A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.
a microscope image of a rotifer
Bacterial Enzyme Keeps Rotifers’ Transposable Elements in Check
Christie Wilcox, PhD | Mar 3, 2022 | 5 min read
Jumping genes in bdelloid rotifers are tamped down by DNA methylation performed by an enzyme pilfered from bacteria roughly 60 million years ago, a study finds.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Composite image showing genes radiating from tumor cells
Jumping Genes’ Role in Cancer
Diana Kwon | Mar 1, 2023 | 8 min read
Transposons may be key players in how tumors develop and spread, but they also keep cancer at bay in some circumstances.
3d rendered medically accurate illustration of a human embryo anatomy
The Ephemeral Life of the Placenta
Danielle Gerhard, PhD | Dec 4, 2023 | 10+ min read
Recent advances in modeling the human placenta, the least understood organ, may inform placental disorders like preeclampsia.
Human DNA abstract dotwork vector illustration made of cloud of colored dots.
Adapting with a Little Help from Jumping Genes
Christie Wilcox, PhD | Jan 17, 2022 | 10+ min read
Long lambasted as junk DNA or genomic parasites, transposable elements turn out to be contributors to adaptation.
Plantsā€™ Epigenetic Secrets
Jef Akst | Feb 1, 2017 | 10+ min read
Unlike animals, plants stably pass on their DNA methylomes from one generation to the next. The resulting gene silencing likely hides an abundance of phenotypic variation.
Methylation: Gene Expression at the Right Place and Right Time
Nadia Halim | Dec 5, 1999 | 7 min read
Courtesy of Richard Roberts, New England BiolabsModel methylation reaction: Cytosine nucleotide (red) is flipped out of the DNA double helix by a methyltransferase (white), so it can be methylated. The end product after the methyl group has been transferred to the DNA is pictured in green. A tenuous link between DNA methylation and development has existed for several years. Now findings substantiate the connection. Researchers have found the first human diseases caused by defects in the DNA meth
RNA repeats protect DNA
Cassandra Brooks | Feb 3, 2010 | 3 min read
Repeat untranscribed DNA sequences are generally thought to be genetic junk at best, harmful at worst, but in ribosomes they are essential to repairing DNA damage, according to a study published this week in Science. Ribosomal protein complex Image: Wikimedia Commons Ribosomal DNA (rDNA) codes for the RNA that makes up a major component of ribosomes, the site of protein synthesis. Ribosomal RNA (rRNA) comprises 80% of the RNA found in a typical cell and is highly conserved from bacteria to hum

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