A key mutation turns healing cells into cancer promoters.

Is DNA damage an inevitable consequence of epigenetic reprogramming?

No two neurons are alike. What does that mean for brain function?

Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).

Microarrays help keep induced pluripotent stem cell lines in check, from start to finish.

Scientists use virus-free gene therapy on patient-derived stem cells to repair spinal muscular atrophy in mice.

Scientists have genetically modified isolated microbes for decades. Now, using CRISPR, they intend to target entire microbiomes.

Several early-stage clinical trials indicate that implanting patients with the cells is safe. But whether they can alleviate neurological problems remains to be seen.

George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.

By Manel Esteller Epigenetic Changes in Cancer The study of how covalent marks on DNA and histones are involved in the origin and spread of cancer cells is also leading to new therapeutic strategies. Lung cancer close-up MOREDUN ANIMAL HEALTH LTD/SPL / Gettyimages Much of the current hype in epigenetics stems from the recognition of its role in human cancer. Yet, intriguingly, the first epigenetic change in human tumors—global genomic DNA hypomethylatio