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tag developmental biology limb development mutations evolution

Losers Fight Back
Richard P. Grant | Feb 1, 2011 | 2 min read
Editor's choice in developmental biology
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
A Simple Genetic Change Adds Limb-Like Bones to Zebrafish Fins
Abby Olena, PhD | Feb 5, 2021 | 4 min read
A gain-of-function mutation in a single gene reveals ancient limb-forming capacity that has been preserved for hundreds of millions of years.
One Protein to Rule Them All
Shelby Bradford, PhD | Feb 28, 2024 | 10+ min read
p53 is possibly the most important protein for maintaining cellular function. Losing it is synonymous with cancer.
Wild water striders (Microvelia longipes) on a puddle. The animals with long third legs are the males; the others are females.
A Multipurpose Gene Facilitates the Evolution of an Animal Weapon
Viviane Callier | May 11, 2021 | 4 min read
A single gene called BMP11 regulates not only the size and proportions of a water strider’s massively long third legs, but also how it uses the limbs in fights.
Monitoring Mutations with Microfluidics
Ruth Williams | Mar 15, 2018 | 3 min read
A device dubbed the “mother machine” enables real-time observation of mutagenesis in single bacterial cells.  
Top 7 in Evolutionary Biology
Jef Akst | Nov 29, 2011 | 3 min read
A snapshot of the most highly ranked articles in evolutionary biology and related areas, from Faculty of 1000
Animalsā€™ Embryonic Organizer Now Discovered in Human Cells
Jim Daley | May 23, 2018 | 4 min read
The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.
Green-tinged image of fly eye with shiny and black portions
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
Jason P. Dinh | Jul 1, 2022 | 4 min read
A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.

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