neuroscience, disease & medicine

A new set of engineered receptors responds to an FDA-approved drug to provide the most potent chemogenetic toolkit to date.

A study in rats finds that tiny doses of the psychedelic drug DMT may yield positive effects for anxiety and depression, but there could be downsides too.

Pathogens can take various routes to pass the blood brain barrier and damage cells.

Scientists may need to seriously reconsider the cast-aside hypothesis that pathogens can play a part in diseases such as Alzheimer’s and Parkinson’s.

Drugs that doctors use to sedate patients during traumatic medical procedures act on neural receptors to alter brain activity.

The protein expression data, which are freely available online, could help identify new drug targets for the disease.

Authors of a small study say the two abilities likely evolved in tandem.

The observation could pave the way for a blood test to predict disease progression in people with a genetic predisposition to developing the neurodegenerative disorder.

Biologists say a sound suspected to have caused headaches, nausea, and possible brain damage among diplomats is actually of insects chirping.

Rodent and human studies have revealed a multitude of effects starting during gestation and lasting into adulthood.

Children born to moms who smoked or ingested marijuana during pregnancy suffer higher rates of depression, hyperactivity, and inattention.

From cellular self-digestion to the effects of exercise on the brain, our features editor picks her favorite art custom-made for the magazine.

The PsychENCODE project delves into the DNA, RNA, and protein changes related to brain development and neuropsychiatric disorders, but researchers caution it’s just a first step toward treatment.

Researchers envision a cochlear implant–like device for the nose to give people with impaired olfaction a sense of smell.

Originally intended for basic neuroscience research, the drugs were ultimately hijacked for illicit recreational use.

The EEG-based method could help clinicians identify patients with severe brain injuries who are actually capable of some cognitive function, despite appearing unresponsive.

This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.

A zebrafish model of the birth defect craniosynostosis provides insights into how the condition develops.

Tau proteins disrupt the movement of molecules into and out of neuronal cells’ nuclei.

Studies have demonstrated that magnetic and electrical currents can enhance memory in human subjects, but the technology is not yet ready for prime time.