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Image of cochlear implant and hearing aid.
Reversing Hearing Loss
Laura Tran, PhD | Nov 1, 2023 | 2 min read
Gene reactivation restored hearing after loss in mice, but the timing of intervention is key.
a medusa-like jellyfish is shown in front of a black background.
The Origins of Hunger Regulation
Mariella Bodemeier Loayza Careaga, PhD | Oct 2, 2023 | 2 min read
A neuropeptide suppressed feeding in two evolutionarily distant species, suggesting that hunger regulation may go back to the roots of the tree of life.
Abstract blue brain image
Integrating Technologies into Neurodegenerative Disease Research
Thermo Fisher Scientific | 1 min read
Genetic analysis techniques give researchers the power to better understand, detect, and treat disease.
A light gray mouse against an orange background listens to tiny headphones
Journey to the Center of the Ear
Niki Spahich, PhD | Aug 28, 2023 | 5 min read
An aqueduct connecting the brain to the ear may make gene therapy for hearing loss less invasive.
MRI images of brains from patients with epilepsy
Defending against Dravet
Aparna Nathan, PhD | Aug 21, 2023 | 3 min read
Gene therapy may be the first step toward curing a rare genetic epilepsy.
TSS
Genomes Across the Tree of Life
The Scientist | 2 min read
Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
Caenorhabditis elegans, a free-living transparent nematode (roundworm), about 1 mm in length.
The Body, Not the Brain, Regulates Sleep
Rebecca Roberts, PhD | Aug 15, 2023 | 3 min read
Genetic screens have revealed three peripheral tissue genes that regulate sleep. What does this mean for sleep research?
iStock
A Way with Words: Using Genomics to Dispel Stuttering Myths
The Scientist | 1 min read
Filling in the gaps about the genetic risk factors of stuttering may help scientists shatter stigmas and discover new therapies.
On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.
Chimera research opens new doors to understanding and treating disease
Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read
Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.
Surreal illustration of the mind, represented by a person-shaped iceberg. A scuba diver illuminates the dark side of the iceberg underwater with a flashlight.
Toward Better Biomarkers for Schizophrenia
Deanna MacNeil, PhD | Aug 7, 2023 | 3 min read
Researchers scratch the surface of schizophrenia susceptibility by uncovering DNA methylation differences in neonatal blood samples.
Challenges and Applications
Combinatorial Single Cell CRISPR Screens: Challenges and Applications
The Scientist Creative Services Team in collaboration with 10x Genomics | 2 min read
An expert panel will discuss how single cell sequencing enhances throughput in CRISPR gene editing applications.
Glass mosaic with the image of two people. The bodies are arbitrarily crossed by lines that divide them into amorphous fractions, some of them colored.
Noninherited Genetic Mutations Link to Schizophrenia
Alejandra Manjarrez, PhD | Jul 20, 2023 | 2 min read
By studying the genomes of more than 24,000 individuals, researchers discovered rare genetic mutations that may shed light on mechanisms underlying schizophrenia.
Researchers in George Church&rsquo;s lab modified wild type ADK proteins (left) in <em >E.coli</em>, furnishing them with an nonstandard amino acid (nsAA) meant to biocontain the resulting bacterial strain.
A Pioneer of The Multiplex Frontier
Rashmi Shivni, Drug Discovery News | May 20, 2023 | 10 min read
George Church is at it again, this time using multiplex gene editing to create virus-proof cells, improve organ transplant success, and protect elephants.
Biomarkers on the Brain: From Sequencing to Functional Imaging
Biomarkers on the Brain: From Sequencing to Functional Imaging
The Scientist | 2 min read
An expert panel will discuss biomarker development for brain disorders and considerations for their clinical use.
A pair of prairie voles (Microtus ochrogaster)
Monogamous Rodents Don’t Need “Love Molecule” To Pair Up
Natalia Mesa, PhD | Jan 27, 2023 | 4 min read
Prairie voles lacking functional receptors for oxytocin form normal social bonds, a finding that could explain the hormone’s clinical failures.
Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Laura Dattaro, Spectrum | Jan 11, 2023 | 4 min read
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
CRISPR Technologies for the New Era of Cell and Gene Therapy
The Scientist | 1 min read
Experts will discuss how they use new CRISPR technologies to advance their cell and gene therapy research.
Illustration of myelinated neuron axons in light blue, with spindly blue and purple cells interspersed among them.
A Gene Variant Linked to Alzheimer’s May Disrupt Myelin Production
Andy Carstens | Nov 22, 2022 | 5 min read
The APOE4 variant causes cholesterol buildup in the cells that make protective fatty sheaths for neurons, possibly helping explain its role in neurodegeneration.
A visualization of a spinal cord with neurons highlighted in red
Scientists Identify Neurons Needed to Walk After Paralysis
Amanda Heidt | Nov 10, 2022 | 3 min read
Nine people with spinal injuries walked again after electrical stimulation, allowing researchers to pinpoint neurons likely underlying their recovery.
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