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Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro
Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro
Genetically engineered cells that overproduce ACE2, the receptor the novel coronavirus uses to enter cells, neutralize infection in vitro and mop up inflammatory cytokines in mice.
Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro
Decoy Cells Trick SARS-CoV-2, Reduce Cytokines In Vitro

Genetically engineered cells that overproduce ACE2, the receptor the novel coronavirus uses to enter cells, neutralize infection in vitro and mop up inflammatory cytokines in mice.

Genetically engineered cells that overproduce ACE2, the receptor the novel coronavirus uses to enter cells, neutralize infection in vitro and mop up inflammatory cytokines in mice.

cell & molecular biology, disease & medicine

Electric and Magnetic Field Treatments Lower Mouse Blood Sugar
Abby Olena, PhD | Oct 9, 2020 | 3 min read
The effects seem to be mediated by a reactive oxygen species in the animals’ livers.
Obituary, University of Oregon, Biochemistry, Molecular Biology, chromatin, chromatin reordering, chromatin reprogramming,
Molecular Biologist Jeff McKnight Dies at 36
Amanda Heidt | Oct 8, 2020 | 3 min read
The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.
Stomach Acid & Heartburn Drugs Linked with COVID-19 Outcomes
Ashley Yeager | Oct 7, 2020 | 6 min read
While sick with COVID-19, President Trump is taking an antacid. Doctors have been exploring whether these medicines can treat SARS-CoV-2 infections, and the results are mixed.
Cheese Preservative Slows Oral Cancer Spread in Mice: Study
Max Kozlov | Oct 1, 2020 | 4 min read
The results add to mounting evidence of microbes’ roles in tumor growth and point to the possibility of impeding malignancies by inhibiting bacteria.
Patients Reinfected with Coronavirus in Hong Kong, Europe
Lisa Winter | Aug 25, 2020 | 2 min read
So far, there are three patients known to have been infected with SARS-CoV-2 twice, and in at least one case the second time around was asymptomatic.
Cold-Causing Coronaviruses Don’t Seem to Confer Lasting Immunity
Shawna Williams | Aug 18, 2020 | 4 min read
Studies on SARS-CoV-2’s milder cousins hint that our immune systems are quick to forget the viruses, but it’s unclear whether the same is true for the agent that causes COVID-19.
Contributors
The Scientist | Jul 13, 2020 | 3 min read
Meet some of the people featured in the July/August 2020 issue of The Scientist.
Luis Alvarez Aims to Heal Wounds with Tissue-Regenerating “Paint”
Shawna Williams | Jul 13, 2020 | 3 min read
The bioactive coating tethers restorative proteins to implanted tissues and fosters new growth, animal studies suggest.
Could Statins Reduce the Severity of COVID-19?
Ashley Yeager | Jun 12, 2020 | 7 min read
The cholesterol-lowering drugs quell inflammation and reverse endothelial tissue damage, hints that they might curb the body’s excessive immune response to SARS-CoV-2 infection.
SARS-CoV-2 Spike Protein Shares Sequence with a Human Protein
Abby Olena, PhD | Jun 1, 2020 | 3 min read
Eight amino acids are identical to part of the human epithelial sodium channel, leading researchers to suspect the virus might interfere with the channel’s function.
Did Contaminated Water Exacerbate Brazilian Babies’ Zika Symptoms?
Ashley Yeager | Jun 1, 2020 | 4 min read
Elevated levels of a neurotoxin in northeastern Brazil’s drinking water and a high incidence of microcephaly in the region led scientists to look for a link, and they found one.
Blood Pressure Meds Point the Way to Possible COVID-19 Treatment
Ashley Yeager | Apr 2, 2020 | 7 min read
There is little evidence that antihypertensive drugs worsen COVID-19, and scientists are instead exploring the idea that such medications—or their downstream effects—may actually alleviate symptoms.
A Trick that Helps Horses and Cattle Avoid Metastatic Cancer
Shawna Williams | Apr 1, 2020 | 2 min read
Researchers find connective tissue has a crucial role to play in whether cancer cells metastasize.
Hadiyah-Nicole Green Targets Cancer With Lasers
Emily Makowski | Apr 1, 2020 | 3 min read
Spurred by family tragedy, the medical physicist wants to treat cancer in a new way.
Cracking Down on Cancer: A Profile of Owen Witte
Diana Kwon | Apr 1, 2020 | 9 min read
Through his studies on cancer-causing viruses, the University of California, Los Angeles, professor has helped develop lifesaving treatments.
Zika as Cancer Buster?
Amy Schleunes | Apr 1, 2020 | 2 min read
By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.
CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity
Amy Schleunes | Mar 24, 2020 | 5 min read
A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.
Lost Smell and Taste Hint COVID-19 Can Target the Nervous System
Ashley Yeager | Mar 24, 2020 | 5 min read
The symptoms suggest SARS-CoV-2 might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths, but the data are preliminary.
Infographic: How Some X-Chromosome Genes Escape Inactivation
Amber Dance | Mar 1, 2020 | 2 min read
About one-quarter of the hundreds of genes on the inactivated X chromosome in XX cells manage to escape that silencing, at least some of the time.
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