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image: Crossing Boundaries

Crossing Boundaries

By | September 1, 2014

A groundbreaker in the study of Listeria monocytogenes, Pascale Cossart continues to build her research tool kit to understand how to fight such intracellular human pathogens.

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image: The Energizer

The Energizer

By | May 1, 2014

György Hajnóczky uncovers the chemical and physical strategies by which mitochondria communicate and function within a cell.

3 Comments

image: Commander of an Immune Flotilla

Commander of an Immune Flotilla

By | April 1, 2014

With much of his early career dictated by US Navy interests, Carl June drew inspiration from malaria, bone marrow transplantation, and HIV in his roundabout path to a breakthrough in cancer immunotherapy.

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image: Biology's Coefficient

Biology's Coefficient

By | December 1, 2013

Joel Cohen uses the tools of mathematics to deconstruct questions of life.

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image: Waste-Management Consultant

Waste-Management Consultant

By | November 1, 2013

By audaciously pursuing an abandoned area of research, Ana María Cuervo discovered how cells selectively break down their waste, and revealed the health consequences when that process malfunctions.

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image: Up, Up, and Array

Up, Up, and Array

By | April 1, 2013

By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.

1 Comment

image: Immune to Failure

Immune to Failure

By | February 1, 2013

With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.

2 Comments

image: An Epi Phenomenon

An Epi Phenomenon

By | December 1, 2012

While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.

5 Comments

image: The Road Less Traveled

The Road Less Traveled

By | November 1, 2012

First, Aravinda Chakravarti drew a map of how scientists might unravel the genetics of complex disease. Then he blazed the trail.

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image: Burgers and Flies

Burgers and Flies

By | May 1, 2012

Inspired by Darwin, Mohamed Noor has uncovered the molecular dance by which a single species becomes two.

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