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image: Up, Up, and Array

Up, Up, and Array

By | April 1, 2013

By scrutinizing gene expression profiles instead of individual oncogenes, Todd Golub launched a powerful platform for diagnosing, classifying, and treating cancer.

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image: Immune to Failure

Immune to Failure

By | February 1, 2013

With dogged persistence and an unwillingness to entertain defeat, Bruce Beutler discovered a receptor that powers the innate immune response to infections—and earned his share of a Nobel Prize.

2 Comments

image: An Epi Phenomenon

An Epi Phenomenon

By | December 1, 2012

While exploring the genetics of a rare type of tumor, Stephen Baylin discovered an epigenetic modification that occurs in most every cancer—a finding he’s helping bring to the clinic.

5 Comments

image: The Road Less Traveled

The Road Less Traveled

By | November 1, 2012

First, Aravinda Chakravarti drew a map of how scientists might unravel the genetics of complex disease. Then he blazed the trail.

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image: (Re)Programming Director

(Re)Programming Director

By | October 1, 2012

Unwilling to accept the finality of terminal differentiation, Helen Blau has honed techniques that showcase the flexibility of cells to adopt different identities.

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image: Hacking the Genome

Hacking the Genome

By | June 1, 2012

In pondering genome structure and function, evolutionary geneticist Laurence Hurst has arrived at some unanticipated conclusions about how natural selection has molded our DNA.

6 Comments

image: Burgers and Flies

Burgers and Flies

By | May 1, 2012

Inspired by Darwin, Mohamed Noor has uncovered the molecular dance by which a single species becomes two.

10 Comments

image: Beyond Expectation

Beyond Expectation

By | September 1, 2011

Philippa “Pippa” Marrack has made some unanticipated discoveries about how the immune system functions in health and disease.

9 Comments

image: Foresight

Foresight

By | July 1, 2011

Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.

12 Comments

Ready, Reset, Go

By | March 1, 2011

Rudolf Jaenisch enjoys climbing mountains, rafting rapids, and unraveling the secrets of pluripotency—knowledge that could someday lead to personalized regenerative medicine.

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