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Spike Structure Gives Insight into SARS-CoV-2 Evolution
Spike Structure Gives Insight into SARS-CoV-2 Evolution
Researchers demonstrate that the SARS-CoV-2 spike protein is more stable and binds the human ACE2 receptor with much higher affinity than the spike protein of its closest known relative, bat coronavirus RaTG13.
Researchers demonstrate that the SARS-CoV-2 spike protein is more stable and binds the human ACE2 receptor with much higher affinity than the spike protein of its closest known relative, bat coronavirus RaTG13.
structural biology, disease & medicine, microbiology
Scientists Scan for Weaknesses in the SARS-CoV-2 Spike Protein
Chris Baraniuk | Apr 9, 2020 | 5 min read
The virus’s tool for prying open host cells is coated in a protective armor of sugar—but gaps may offer vulnerability to disruption by antibodies.