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tag art genomics policy trump

Sequencing Stakes: Celera Genomics Carves Its Niche
Ricki Lewis | Jul 18, 1999 | 8 min read
J. Craig Venter is no stranger to contradiction and controversy. He seems to thrive on it. In 1991, when the National Institutes of Health was haggling over patenting expressed sequence tags (ESTs)--a shortcut to identifying protein-encoding genes--Venter the inventor accepted a private offer to found The Institute for Genomic Research (TIGR) in Rockville, Md. TIGR would discover ESTs and give most of them to a commercial sibling, Human Genome Sciences (HGS), to market. ESTs are now a standard
Genome Investigator Craig Venter Reflects On Turbulent Past And Future Ambitions
Karen Young Kreeger | Jul 23, 1995 | 8 min read
And Future Ambitions Editor's Note: For the past four years, former National Institutes of Health researcher J. Craig Venter has been a major figure in the turbulent debates and scientific discoveries surrounding the study of genes and genomes. Events heated up in 1991, when NIH attempted to patent gene fragments, which were isolated using Venter's expressed sequence tag (EST)/complementary DNA (cDNA) approach for discovering human genes (M.A. Adams et al., Science, 252:1651-6, 1991). NIH's mo
Privatizing the Human Genome?
Paul Smaglik | Jun 7, 1998 | 10 min read
Principals behind joint-venture proposal and public effort seek to define relationships A private effort to sequence the human genome four years ahead of the Human Genome Project's 2005 goal could either compete directly with the federal project or meld seamlessly with it. Before any relationship between the two efforts becomes formalized, scientists and federal officials involved with the Human Genome Project must determine whether the private approach will work, who will own the data, how qu
Will Genomics Spoil Gene Ownership?
Douglas Steinberg | Sep 3, 2000 | 8 min read
Consider a scenario for the year 2002: Using commercially available software, bioprospector "Craig Collins" spends a day scavenging the Human Genome Project (HGP) database for the alternatively spliced genes prized by Wall Street. He enters the sequences of several candidate genes into a software package that prints out the likely functions of their protein products. One protein looks like it could be pharmaceutical paydirt, so he isolates the corresponding cDNA, inserts it into a vector, then
Single Nucleotide Polymorphisms: Big Pharma Hedges its Bets
Eugene Russo | Jul 18, 1999 | 7 min read
SNP CENTRAL: A genetics researcher takes to the bench at the Wellcome Trust's Sanger Centre in Cambridge, England. The sequencing center and its London sponsor provided key leadership in the SNP Consortium, a public-private venture to find and map 300,000 single nucleotide polymorphisms. The Wellcome Trust helped entice 10 pharmaceutical firms to join the consortium by putting up $14 million of the project's estimated $45 million price tag. The Sanger Centre will provide much of the radiation h
Clinton, Blair Stoke Debate on Gene Data
Ricki Lewis | Apr 2, 2000 | 7 min read
President Bill Clinton and British Prime Minister Tony Blair's brief statement of March 14 supporting free access to human genome information unleashed a slew of clichés, including "too little too late" and "water under the bridge." But initial misinterpretation of the statement led to a temporary slide in biotech stocks. By the end of the day, Celera Genomics Corp. of Rockville, Md., had dropped 19 percent, while Incyte Pharmaceuticals of Palo Alto, Calif., plummeted 27 percent. Even thoug
Top 10 Innovations 2016
The Scientist | Dec 1, 2016 | 10+ min read
This year’s list of winners celebrates both large leaps and small (but important) steps in life science technology.
The Biggest Stories in Bioscience 2005
Ishani Ganguli | Dec 4, 2005 | 8 min read
Life scientists have been challenged more than ever this year not just to critically analyze data, but to better interpret those data for an increasingly critical public.
Notebook
The Scientist Staff | Mar 2, 1997 | 8 min read
Monday mornings can be tough, even if you're Bill Gates. The head of Redmond, Wash.-based Microsoft Corp. ran into a few glitches at a presentation he was giving at the annual meeting of the American Association for the Advancement of Science (AAAS) in Seattle. In the middle of a demonstration on February 17 aimed at showing how Web browsers and E-mail will soon merge, the modem connection failed. A computer-vision demonstration by a Microsoft researcher didn't work, either. Then, during a ques
Today's Lab
Laura Defrancesco | Mar 3, 2002 | 8 min read
Tom Sargent remembers the day a student in his lab forgot to add boiling chips to phenol before firing up the heater on the distillation apparatus, and the panicked shouting and tearing off of the lab coat, goggles, gloves, and shoes that ensued when the phenol superheated and boiled over. "Fortunately he wasn't hurt," said Sargent, now chief of the section on vertebrate development at the National Institute of Child and Human Development, "but what a mess." Then, there was the time he hooked up

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