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early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

disease & medicine, DNA

Gloria Echeverria Investigates an Insidious Form of Breast Cancer
Max Kozlov | Dec 1, 2020 | 3 min read
The newly minted Baylor College of Medicine faculty member is working to crack the mystery of triple negative breast cancer.
New Map Charts Genetic Expression Across Tissue Types, Sexes
Ashley Yeager | Sep 10, 2020 | 3 min read
A decade-long effort to probe gene regulation reveals differences between males and females, points to essential regulatory elements, and offers insight into past work on telomeres.
Revealing the Complexities of Cancer with Single-cell RNA Analysis
The Scientist | Aug 19, 2020 | 1 min read
Download this eBook to learn how single-cell analysis identifies subpopulations of tumor cells!
For the Greater Good: A Profile of Eva Harris
Diana Kwon | Jul 13, 2020 | 10 min read
Through groundbreaking studies on dengue and efforts to build scientific infrastructure in Latin America, the University of California, Berkeley, professor has bridged research with its benefits to society.
Novel DNA-Sensing Pathway Found in Human Cells, Absent in Mice
Catherine Offord | Jan 24, 2020 | 4 min read
This previously unknown mechanism for spotting foreign genetic material in the cytoplasm launches antiviral defenses even when the well-known immune mediator STING is absent.
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019 | 3 min read
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
Mouse club cells
Image of the Day: Resilient Lung Cells
Nicoletta Lanese | Aug 1, 2019 | 1 min read
A specific type of lung cell withstands flu infection by doubling down on DNA repair.
NIH Announces Details of Human Fetal Tissue Research Restrictions
Ashley Yeager | Jul 29, 2019 | 2 min read
The latest restrictions require scientists to submit more comprehensive grant applications, and those applications will go through more stringent ethics reviews.
Stuart Orkin
In Our Blood: A Profile of Stuart Orkin
Anna Azvolinsky | Jul 15, 2019 | 9 min read
By unraveling the molecular underpinnings of inherited blood disorders, the Boston Children’s Hospital researcher has provided the basis for therapies now being tested for beta-thalassemia and sickle cell disease.
micro needle patch plant disease diagnostic diagnosis DNA extraction plants
Image of the Day: Holey Leaves
Chia-Yi Hou | Jun 13, 2019 | 1 min read
Scientists use microneedle patches to extract DNA for diagnosing diseases in plants.
Allele Shows Pyrethroid Resistance’s Spread in African Mosquitos
Carolyn Wilke | Mar 22, 2019 | 4 min read
Researchers can now track the expansion of a resistance mechanism that allows the malaria vector Anopholes funestus to detoxify a key insecticide used on bed nets.
Electric Shock Allows for CRISPR Gene Editing Without a Viral Vector
Ashley Yeager | Jul 12, 2018 | 2 min read
Brief electroporation appears to make T cells more receptive to new genetic material, which could speed the development of immunotherapies.
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