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tag policy politics art genetics genomics

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Iconic Geneticist Evelyn Witkin Dies at Age 102
Lisa Winter | Jul 24, 2023 | 3 min read
Lasker Award winner Evelyn Witkin discovered the mechanism for DNA repair following UV damage.
Genetic Testing's Political Implications Must Be Addressed
Dan Burk | Jul 20, 1997 | 6 min read
The recent public apology by President Clinton on behalf of the United States government to survivors of the Tuskegee syphilis experiments was intended to close the door on one of the most scandalous instances of officially sanctioned scientific misconduct in the annals of biomedical research. Yet, while the apology may bring closure to the particular incident, it stands as a stark reminder of the history that has led many minorities to distrust supposedly objective scientific research. Betraye
Scientists Struggling With Concerns Raised By Genome Project Progress
Steven Benowitz | Jul 7, 1996 | 10+ min read
Genome Project Progress Some firms and institutions are establishing ethics branches to focus on policy issues left unresolved by NIH's ELSI project. RULES REQUIRED: Stanford's Paul Billings thinks ELSI has fallen short in creating a "regulatory arena". Many scientists are finding that concerns about the complex ethical, legal, and social issues surrounding genetic testing and the use of the resulting information are taking up a larger part of their time. In response to this shift in focus,
Toward a “Clickable Plant”
Jane Salodof Macneil | Feb 15, 2004 | 9 min read
By conscious design, plant genomics initiatives have devoted initial resources to new technology development. Part of that money went to developing functional genomics approaches, and part to new sequencing technologies.
Sequencing Stakes: Celera Genomics Carves Its Niche
Ricki Lewis | Jul 18, 1999 | 8 min read
J. Craig Venter is no stranger to contradiction and controversy. He seems to thrive on it. In 1991, when the National Institutes of Health was haggling over patenting expressed sequence tags (ESTs)--a shortcut to identifying protein-encoding genes--Venter the inventor accepted a private offer to found The Institute for Genomic Research (TIGR) in Rockville, Md. TIGR would discover ESTs and give most of them to a commercial sibling, Human Genome Sciences (HGS), to market. ESTs are now a standard
Genome Investigator Craig Venter Reflects On Turbulent Past And Future Ambitions
Karen Young Kreeger | Jul 23, 1995 | 8 min read
And Future Ambitions Editor's Note: For the past four years, former National Institutes of Health researcher J. Craig Venter has been a major figure in the turbulent debates and scientific discoveries surrounding the study of genes and genomes. Events heated up in 1991, when NIH attempted to patent gene fragments, which were isolated using Venter's expressed sequence tag (EST)/complementary DNA (cDNA) approach for discovering human genes (M.A. Adams et al., Science, 252:1651-6, 1991). NIH's mo
Privatizing the Human Genome?
Paul Smaglik | Jun 7, 1998 | 10 min read
Principals behind joint-venture proposal and public effort seek to define relationships A private effort to sequence the human genome four years ahead of the Human Genome Project's 2005 goal could either compete directly with the federal project or meld seamlessly with it. Before any relationship between the two efforts becomes formalized, scientists and federal officials involved with the Human Genome Project must determine whether the private approach will work, who will own the data, how qu
Prometheus' Fire: Sharing The Responsibility
Joshua Lederberg | Jan 20, 1991 | 2 min read
In enduring myth, Prometheus was severely punished for giving humankind "every art and science"--the power to defy the forces of Nature. This concern about forbidden knowledge survives today. It is aggravated by inquiry that is both arcane and intensive, as research into DNA, genetic engineering, and the human genome is purported to be. This public anxiety persists despite general satisfaction over the economic and life-extending benefits of scientific progress. Scientific expertise offers a u
Will Genomics Spoil Gene Ownership?
Douglas Steinberg | Sep 3, 2000 | 8 min read
Consider a scenario for the year 2002: Using commercially available software, bioprospector "Craig Collins" spends a day scavenging the Human Genome Project (HGP) database for the alternatively spliced genes prized by Wall Street. He enters the sequences of several candidate genes into a software package that prints out the likely functions of their protein products. One protein looks like it could be pharmaceutical paydirt, so he isolates the corresponding cDNA, inserts it into a vector, then
Reproductive Research Progresses Despite Restrictions
Sara Latta | Mar 1, 1998 | 8 min read
While the ethics of human cloning has dominated recent discussion of reproductive technologies, research involving human embryos has always been a political hot potato, entangled with the twin issues of abortion and the beginning of human life. Restrictive policies and negative public attitudes surrounding embryo research have made it increasingly difficult for the infertility research community to improve the success rates for assisted reproductive technologies. According to the Centers for Di

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