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tag immunology structural biology cancer cell molecular biology

Microfluidics: Biology’s Liquid Revolution
Laura Tran, PhD | Feb 26, 2024 | 8 min read
Microfluidic systems redefined biology by providing platforms that handle small fluid volumes, catalyzing advancements in cellular and molecular studies.
3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
Infusion of Artificial Intelligence in Biology
Meenakshi Prabhune, PhD | Feb 23, 2024 | 10 min read
With deep learning methods revolutionizing life sciences, researchers bet on de novo proteins and cell mapping models to deliver customized precision medicines.
Molecular Biology
The Scientist Staff | Jul 24, 1994 | 2 min read
D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257:919-27, 1992. Ian A. Wilson (Department of Molecular Biology, Scripps Research Institute, La Jolla, Calif.): "One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can
Molecular Biology
The Scientist Staff | Jul 24, 1994 | 2 min read
D.H. Fremont, M. Matsumura, E.A. Stura, P.A. Peterson, I.A. Wilson, "Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb," Science, 257:919-27, 1992. Ian A. Wilson (Department of Molecular Biology, Scripps Research Institute, La Jolla, Calif.): "One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can
Molecular Biology
The Scientist Staff | Oct 27, 1991 | 2 min read
S.J. Rhodes, S.F. Konieczny, "Identification of MRF4: a new member of the muscle regulatory factor gene family," Genes & Development, 3:2050-61, 1989. Stephen F. Konieczny (Purdue University, West Lafayette, Ind.): "This paper describes the identification and characterization of MRF4, the fourth member of a structurally and functionally related family of muscle regulatory factors that includes MyoD, myogenin, and Myf-5. Forced expression of MRF4 in fibroblasts converts nonmuscle cells to skele
Structural Biology
The Scientist Staff | Mar 2, 1997 | 2 min read
Edited by: Karen Young Kreeger J.P. Griffith, J.L. Kim, E.E. Kim, M.D. Sintchak, J.A. Thomson, M.J. Fitzgibbon, M.A. Fleming, P.R. Caron, K. Hsiao, M.A. Navia, "X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex," Cell, 82:507-22, 1995. (Cited in close to 70 publications as of February 1997) Comments by James P. Griffith and Joseph L. Kim, Vertex Pharmaceuticals Inc., Cambridge, Mass. FK506 is an immunosuppressant drug used for preventing graft
Molecular Biology
The Scientist Staff | Dec 9, 1990 | 1 min read
S. Hahn, S. Buratowski, P.A. Sharp, L. Guarente, "Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions," Cell, 58, 1173-81, 22 September 1989. Steven Hahn (Fred Hutchinson Cancer Research Center, Seattle): "TFIID is one of the essential components in the machinery necessary to initiate transcription by RNA polymerase II. For eight years after the discovery of TFIID in mammals, little was known about it because of
MOLECULAR BIOLOGY
The Scientist Staff | Dec 8, 1991 | 2 min read
MOLECULAR BIOLOGY Date: December 9, 1991 D. Anderson, C.A. Koch, L. Grey, C. Ellis, et al., "Binding of SH2 domains of phospholipase Cg1, GAP, and Src to activated growth factor receptors," Science, 250:979-82, 1990. Tony Pawson (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto): "Many of the hormones that control cell growth, differentiation, and metabolism in the adult, and development in the embryo, bind to the extracellular region of receptors that span th
DNA molecule.
Finding DNA Tags in AAV Stacks
Mariella Bodemeier Loayza Careaga, PhD | Mar 7, 2024 | 8 min read
Ten years ago, scientists put DNA barcodes in AAV vectors, creating an approach that simplified, expedited, and streamlined AAV screening. 

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